A Rare Case of Human Coronavirus 229E Associated with Acute Respiratory Distress Syndrome in a Healthy Adult
Joint Authors
Vassilara, Foula
Spyridaki, Aikaterini
Pothitos, George
Deliveliotou, Athanassia
Papadopoulos, Antonios
Source
Case Reports in Infectious Diseases
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-15
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Human coronavirus 229E (HCoV-229E) is one of the first coronavirus strains being described.
It is linked to common cold symptoms in healthy adults.
Younger children and the elderly are considered vulnerable to developing lower respiratory tract infections (LRTIs).
In particular, immunocompromised patients have been reported with severe and life-threatening LRTIs attributed to HCoV-229E.
We report for the first time a case of LRTI and acute respiratory distress syndrome developed in a healthy adult with no comorbidities and HCoV-229E strain identified as the only causative agent.
A 45-year-old female with a clear medical history presented with fever, cough, and headache.
Respiratory tract infection was diagnosed, and empirical antibiotics were started.
Within two days, she developed bilateral pleural effusions, diffuse consolidations, and ground glass opacities involving all lung fields.
She needed immediate oxygen supply, while ABGs deteriorated and chest imaging and PaO2/FiO2 indicated ARDS.
Early administration of systemic corticosteroids led to gradual clinical improvement.
Multiplex PCR from nasal secretions was positive only for HCoV-229E and negative for multiple other pathogens.
It remains to be elucidated how an immunocompetent adult developed a life-threatening LRTI caused by a “benign considered” coronavirus strain, the HCoV-229E.
American Psychological Association (APA)
Vassilara, Foula& Spyridaki, Aikaterini& Pothitos, George& Deliveliotou, Athanassia& Papadopoulos, Antonios. 2018. A Rare Case of Human Coronavirus 229E Associated with Acute Respiratory Distress Syndrome in a Healthy Adult. Case Reports in Infectious Diseases،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144621
Modern Language Association (MLA)
Vassilara, Foula…[et al.]. A Rare Case of Human Coronavirus 229E Associated with Acute Respiratory Distress Syndrome in a Healthy Adult. Case Reports in Infectious Diseases No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1144621
American Medical Association (AMA)
Vassilara, Foula& Spyridaki, Aikaterini& Pothitos, George& Deliveliotou, Athanassia& Papadopoulos, Antonios. A Rare Case of Human Coronavirus 229E Associated with Acute Respiratory Distress Syndrome in a Healthy Adult. Case Reports in Infectious Diseases. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144621
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144621