Analysis and Research of Key Genes in Gene Expression Network Based on Complex Network

Joint Authors

Chen, Guobin
Wu, Yongzhong
Shi, Xiaolong
Tang, Chao
Wang, Ying
Qi, Jun

Source

Complexity

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-12, 12 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-12-10

Country of Publication

Egypt

No. of Pages

12

Main Subjects

Philosophy

Abstract EN

Gene expression network is also a type of complex network.

It is challenging to analyze the gene expression network through relevant knowledge and algorithms of a complex network.

In this paper, the existing characteristics of genes are analyzed from various indexes of the gene expression network to analyze key genes and TOP genes.

Firstly, gene chip data are screened, gene data with obvious characteristics are selected, and relevant clustering characteristics are analyzed.

Then, the complex gene network structure is established, and gene networks with different threshold shapes and different sizes are selected.

Finally, the relevant indexes and PR values after the PageRank algorithm are analyzed for complex networks under different thresholds, thus establishing the TOP gene and PR sequence.

American Psychological Association (APA)

Chen, Guobin& Qi, Jun& Tang, Chao& Wang, Ying& Wu, Yongzhong& Shi, Xiaolong. 2020. Analysis and Research of Key Genes in Gene Expression Network Based on Complex Network. Complexity،Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1144642

Modern Language Association (MLA)

Chen, Guobin…[et al.]. Analysis and Research of Key Genes in Gene Expression Network Based on Complex Network. Complexity No. 2020 (2020), pp.1-12.
https://search.emarefa.net/detail/BIM-1144642

American Medical Association (AMA)

Chen, Guobin& Qi, Jun& Tang, Chao& Wang, Ying& Wu, Yongzhong& Shi, Xiaolong. Analysis and Research of Key Genes in Gene Expression Network Based on Complex Network. Complexity. 2020. Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1144642

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1144642