Toxoplasma Encephalitis following Tandem Autologous Hematopoietic Stem Cell Transplantation: A Case Report and Review of the Literature
Joint Authors
Tricot, Guido
Kollu, Vidya
Magalhaes-Silverman, Margarida
Ince, Dilek
Source
Case Reports in Infectious Diseases
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-11
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Infection with Toxoplasma gondii is a rare but often fatal complication in hematopoietic stem cell transplantation (HSCT) recipients.
Most cases have been reported in allogeneic (allo-) HSCT recipients, with only narrative reports following autologous HSCT (ASCT).
We report the case of a 58-year-old Caucasian male presenting with toxoplasma encephalitis following tandem ASCT for myeloma and successfully treated with diagnosis by polymerase chain reaction analysis of cerebrospinal fluid.
He was treated with sulfadiazine and pyrimethamine (with leucovorin) followed by pyrimethamine and atovaquone as secondary prophylaxis while receiving subsequent therapy for progressive multiple myeloma.
Toxoplasmosis is a potential complication in allo-HSCT as well as ASCT recipients and should be considered in any post-HSCT patient with neurological dysfunction.
Rapid diagnosis and immediate antimicrobial treatment are essential to avoid morbidity and mortality.
American Psychological Association (APA)
Kollu, Vidya& Magalhaes-Silverman, Margarida& Tricot, Guido& Ince, Dilek. 2018. Toxoplasma Encephalitis following Tandem Autologous Hematopoietic Stem Cell Transplantation: A Case Report and Review of the Literature. Case Reports in Infectious Diseases،Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1144704
Modern Language Association (MLA)
Kollu, Vidya…[et al.]. Toxoplasma Encephalitis following Tandem Autologous Hematopoietic Stem Cell Transplantation: A Case Report and Review of the Literature. Case Reports in Infectious Diseases No. 2018 (2018), pp.1-3.
https://search.emarefa.net/detail/BIM-1144704
American Medical Association (AMA)
Kollu, Vidya& Magalhaes-Silverman, Margarida& Tricot, Guido& Ince, Dilek. Toxoplasma Encephalitis following Tandem Autologous Hematopoietic Stem Cell Transplantation: A Case Report and Review of the Literature. Case Reports in Infectious Diseases. 2018. Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1144704
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144704