Successful Treatment of Methampyrone-Induced Toxic Epidermal Necrolysis with Therapeutic Plasma Exchange
Joint Authors
Santosa, Thomas R.
Rumbiana, A.
Wahab, Z.
Kurniawan, S. P.
Naibaho, R. M.
Yogyartono, P.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-18
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The toxic epidermal necrolysis (TEN) is a severe cutaneous adverse reaction frequently caused by drug exposure.
A 58-year-old male was admitted to the hospital after administration of methampyrone.
He developed sloughing of the total epidermis which rapidly extended over the trunk and limbs.
The presumptive diagnosis was drug-induced TEN.
Despite the treatment with pulsed glucocorticoid and cyclosporine, the skin lesions extended over the entire body.
Strikingly, the progression of blistering was stopped by therapeutic plasma exchange (TPE).
TPE was discontinued after the signs of skin inflammation had been overcome.
He recovered in 8 days of hospitalization.
We present here a case of a methampyrone-induced TEN which was successfully treated with TPE.
American Psychological Association (APA)
Santosa, Thomas R.& Rumbiana, A.& Wahab, Z.& Kurniawan, S. P.& Naibaho, R. M.& Yogyartono, P.. 2018. Successful Treatment of Methampyrone-Induced Toxic Epidermal Necrolysis with Therapeutic Plasma Exchange. Case Reports in Medicine،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144811
Modern Language Association (MLA)
Santosa, Thomas R.…[et al.]. Successful Treatment of Methampyrone-Induced Toxic Epidermal Necrolysis with Therapeutic Plasma Exchange. Case Reports in Medicine No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1144811
American Medical Association (AMA)
Santosa, Thomas R.& Rumbiana, A.& Wahab, Z.& Kurniawan, S. P.& Naibaho, R. M.& Yogyartono, P.. Successful Treatment of Methampyrone-Induced Toxic Epidermal Necrolysis with Therapeutic Plasma Exchange. Case Reports in Medicine. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144811
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144811