A Giant-Cell Lesion with Cellular Cannibalism in the Mandible: Case Report and Review of Brown Tumors in Hyperparathyroidism
Joint Authors
Azzi, Lorenzo
Cimetti, Laura
Annoni, Matteo
Anselmi, Diego
Tettamanti, Lucia
Tagliabue, Angelo
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-09
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
A small radiolucent area in the mandible was discovered in a 58-year-old woman with no oral complaints.
The patient’s history included only hypertension.
The lesion was considered as an inflammatory cyst and was enucleated.
Three months later, a CT revealed the presence of a cyst-like lesion in the mandible with thin expanded buccal cortical plate, localized erosion, and a polylobate appearance on the lingual aspect of the cortical plate.
The histological diagnosis of the lesion was central giant-cell granuloma (CGCG).
The lesion was thoroughly enucleated.
Nevertheless, another X-ray carried out six months later revealed multiple bilateral osteolytic areas throughout the jaw.
In addition, widespread cortical plate erosion was observed, as well as signs of root resorption and periodontal enlargement.
There was no sign of neurological involvement, although the nerves appeared to be dislocated.
After full blood chemistry analysis and detailed collection of radiographs, the final diagnosis was brown tumors in primary hyperparathyroidism.
This case report demonstrates how dental clinicians may be the first-line specialists who identify a complex systemic disease before other clinicians.
Finally, it highlights the role of cellular cannibalism in predicting the clinical aggressiveness of brown tumors as well as in other giant-cell lesions.
American Psychological Association (APA)
Azzi, Lorenzo& Cimetti, Laura& Annoni, Matteo& Anselmi, Diego& Tettamanti, Lucia& Tagliabue, Angelo. 2017. A Giant-Cell Lesion with Cellular Cannibalism in the Mandible: Case Report and Review of Brown Tumors in Hyperparathyroidism. Case Reports in Dentistry،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1144895
Modern Language Association (MLA)
Azzi, Lorenzo…[et al.]. A Giant-Cell Lesion with Cellular Cannibalism in the Mandible: Case Report and Review of Brown Tumors in Hyperparathyroidism. Case Reports in Dentistry No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1144895
American Medical Association (AMA)
Azzi, Lorenzo& Cimetti, Laura& Annoni, Matteo& Anselmi, Diego& Tettamanti, Lucia& Tagliabue, Angelo. A Giant-Cell Lesion with Cellular Cannibalism in the Mandible: Case Report and Review of Brown Tumors in Hyperparathyroidism. Case Reports in Dentistry. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1144895
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144895