The Wolf Hidden behind the Clots: Catastrophic Antiphospholipid Antibody Syndrome
Joint Authors
Agarwal, K. A.
Soe, Myat Han
Akough-Weir, Alueshima
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-19
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Catastrophic antiphospholipid syndrome (CAPS) is a rare but highly fatal clinical syndrome that occurs in up to 1% of patients with antiphospholipid syndrome (APS).
The diagnosis of CAPS is often delayed because its presentation with multiple organ thromboses can be confused with other thrombotic microangiopathies and severe sepsis.
We report a case of CAPS in a patient with APS and systemic lupus erythematosus (SLE) presenting with thrombotic storm precipitated by trauma, cytomegalovirus (CMV) infection, and noncompliance with anticoagulation therapy.
Our case reflects the “two-hit hypothesis” of APS in which the presence of antiphospholipid antibodies (first hit) increases the thrombophilic risk, and thromboses take place in the presence of another thrombophilic condition such as CMV infection in our case.
In this case review, we discuss the diagnostic challenges and management of CAPS.
In clinical practice, we aim to stress the importance of thorough evaluation and management of precipitating events such as infections in addition to timely diagnosis and treatment of this catastrophic clinical entity.
American Psychological Association (APA)
Soe, Myat Han& Agarwal, K. A.& Akough-Weir, Alueshima. 2018. The Wolf Hidden behind the Clots: Catastrophic Antiphospholipid Antibody Syndrome. Case Reports in Medicine،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144919
Modern Language Association (MLA)
Soe, Myat Han…[et al.]. The Wolf Hidden behind the Clots: Catastrophic Antiphospholipid Antibody Syndrome. Case Reports in Medicine No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1144919
American Medical Association (AMA)
Soe, Myat Han& Agarwal, K. A.& Akough-Weir, Alueshima. The Wolf Hidden behind the Clots: Catastrophic Antiphospholipid Antibody Syndrome. Case Reports in Medicine. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144919
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144919