Lactate Gap: A Diagnostic Support in Severe Metabolic Acidosis of Unknown Origin
Joint Authors
Nielsen, Erik Waage
Hauvik, Linn E.
Varghese, Mercy
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-24
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Ethylene glycol poisoning is a medical emergency.
The metabolites glycolate and glyoxylate give metabolic acidosis.
Because of similar structure, these metabolites are misinterpreted as lactate by many point-of-care blood gas analyzers.
The falsely high lactate values can lead to misdiagnosis, inappropriate laparotomies, and delayed antidotal therapy.
As laboratory analyzers measure plasma lactate only, the difference or the “lactate gap” aids in early diagnosis.
We present a patient with severe metabolic acidosis and elevated lactate levels on the point-of-care analyzer.
A lactate gap supported the diagnosis of ethylene glycol poisoning.
Hemodialysis and fomepizole treatment could be started immediately.
American Psychological Association (APA)
Hauvik, Linn E.& Varghese, Mercy& Nielsen, Erik Waage. 2018. Lactate Gap: A Diagnostic Support in Severe Metabolic Acidosis of Unknown Origin. Case Reports in Medicine،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144949
Modern Language Association (MLA)
Hauvik, Linn E.…[et al.]. Lactate Gap: A Diagnostic Support in Severe Metabolic Acidosis of Unknown Origin. Case Reports in Medicine No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1144949
American Medical Association (AMA)
Hauvik, Linn E.& Varghese, Mercy& Nielsen, Erik Waage. Lactate Gap: A Diagnostic Support in Severe Metabolic Acidosis of Unknown Origin. Case Reports in Medicine. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144949
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144949