PUVA Induced Bullous Pemphigoid in a Patient with Mycosis Fungoides
Joint Authors
Başsorgun, Cumhur İbrahim
Ozkesici, Birgul
Koç, Saliha
Akman-Karakaş, Ayşe
Yılmaz, Ertan
Uzun, S.
Source
Case Reports in Dermatological Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-16
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Background.
Bullous pemphigoid is an autoimmune subepidermal blistering skin disease in which autoantibodies are directed against components of the basement membrane.
The disease primarily affects the elderly people and in most of the patients inducing factors cannot be identified.
Herein, we report a case of BP that occurred in a patient who was receiving PUVA therapy for the treatment of mycosis fungoides.
Main Observation.
A 26-year-old woman with mycosis fungoides developed blisters while receiving PUVA therapy.
On physical examination tense bullae on the normal skin, remnants of blisters, and erosions were observed on her breasts, the chest wall, and the upper abdomen.
Histopathological investigations revealed subepidermal blisters with eosinophilic infiltration and in direct immunofluorescence examination linear deposition of IgG along the basement membrane zone was observed.
The diagnosis of bullous pemphigoid was also confirmed by ELISA and BIOCHIP mosaic-based indirect immunofluorescence test.
Conclusions.
PUVA therapy is an extremely rare physical factor capable of inducing bullous pemphigoid.
So the development of blistering lesions during PUVA therapy may be suggestive sign of a bullous disease such as bullous pemphigoid and it should be excluded with proper clinical and laboratory approaches immediately after withdrawal of PUVA therapy.
American Psychological Association (APA)
Ozkesici, Birgul& Koç, Saliha& Akman-Karakaş, Ayşe& Yılmaz, Ertan& Başsorgun, Cumhur İbrahim& Uzun, S.. 2017. PUVA Induced Bullous Pemphigoid in a Patient with Mycosis Fungoides. Case Reports in Dermatological Medicine،Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1144988
Modern Language Association (MLA)
Ozkesici, Birgul…[et al.]. PUVA Induced Bullous Pemphigoid in a Patient with Mycosis Fungoides. Case Reports in Dermatological Medicine No. 2017 (2017), pp.1-3.
https://search.emarefa.net/detail/BIM-1144988
American Medical Association (AMA)
Ozkesici, Birgul& Koç, Saliha& Akman-Karakaş, Ayşe& Yılmaz, Ertan& Başsorgun, Cumhur İbrahim& Uzun, S.. PUVA Induced Bullous Pemphigoid in a Patient with Mycosis Fungoides. Case Reports in Dermatological Medicine. 2017. Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1144988
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144988