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A Rapidly Fatal Case of Low-Dose Methotrexate Toxicity
Joint Authors
Raj, Rishi
Shaikh, Nasreen
Sardar, Muhammad
Jariwala, Punit
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-13
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
An 82-year-old female presented with multiple oral ulcers and malena for 1 week.
Her laboratory tests revealed pancytopenia and acute renal failure.
She had history of rheumatoid arthritis for which she was taking 7.5 mg methotrexate weekly and stage 4 chronic kidney disease from diabetic nephropathy.
During the hospital stay, she developed pneumonia and septic shock requiring norepinephrine and vasopressin.
She underwent continuous venovenous hemodiafiltration.
Leucovorin, filgrastim, and multiple packed red blood cell and platelet transfusions were given.
She remained hypotensive and pancytopenic despite all interventions.
She died on day 6 of hospital stay from acute hypoxic respiratory failure due to septic shock.
American Psychological Association (APA)
Shaikh, Nasreen& Sardar, Muhammad& Raj, Rishi& Jariwala, Punit. 2018. A Rapidly Fatal Case of Low-Dose Methotrexate Toxicity. Case Reports in Medicine،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1145107
Modern Language Association (MLA)
Shaikh, Nasreen…[et al.]. A Rapidly Fatal Case of Low-Dose Methotrexate Toxicity. Case Reports in Medicine No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1145107
American Medical Association (AMA)
Shaikh, Nasreen& Sardar, Muhammad& Raj, Rishi& Jariwala, Punit. A Rapidly Fatal Case of Low-Dose Methotrexate Toxicity. Case Reports in Medicine. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1145107
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145107