A Rapidly Fatal Case of Low-Dose Methotrexate Toxicity

Joint Authors

Raj, Rishi
Shaikh, Nasreen
Sardar, Muhammad
Jariwala, Punit

Source

Case Reports in Medicine

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-06-13

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Medicine

Abstract EN

An 82-year-old female presented with multiple oral ulcers and malena for 1 week.

Her laboratory tests revealed pancytopenia and acute renal failure.

She had history of rheumatoid arthritis for which she was taking 7.5 mg methotrexate weekly and stage 4 chronic kidney disease from diabetic nephropathy.

During the hospital stay, she developed pneumonia and septic shock requiring norepinephrine and vasopressin.

She underwent continuous venovenous hemodiafiltration.

Leucovorin, filgrastim, and multiple packed red blood cell and platelet transfusions were given.

She remained hypotensive and pancytopenic despite all interventions.

She died on day 6 of hospital stay from acute hypoxic respiratory failure due to septic shock.

American Psychological Association (APA)

Shaikh, Nasreen& Sardar, Muhammad& Raj, Rishi& Jariwala, Punit. 2018. A Rapidly Fatal Case of Low-Dose Methotrexate Toxicity. Case Reports in Medicine،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1145107

Modern Language Association (MLA)

Shaikh, Nasreen…[et al.]. A Rapidly Fatal Case of Low-Dose Methotrexate Toxicity. Case Reports in Medicine No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1145107

American Medical Association (AMA)

Shaikh, Nasreen& Sardar, Muhammad& Raj, Rishi& Jariwala, Punit. A Rapidly Fatal Case of Low-Dose Methotrexate Toxicity. Case Reports in Medicine. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1145107

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1145107