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Atypical Haemolytic Uraemic Syndrome Associated with Clostridium difficile Infection Successfully Treated with Eculizumab
Joint Authors
Barbara, Jeffrey
Inglis, Joshua M.
Juneja, Rajiv
Milton, Caroline
Passaris, George
Li, Jordan Y. Z.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-10
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Clostridium difficile infection is a rare precipitant of atypical haemolytic uraemic syndrome (aHUS).
A 46-year-old man presented with watery diarrhoea following an ileocaecal resection.
He developed an acute kidney injury with anaemia, thrombocytopaenia, raised lactate dehydrogenase, low haptoglobin, and red cell fragments.
Stool sample was positive for C.
difficile toxin B.
He became dialysis-dependent as his renal function continued to worsen despite treatment with empiric antibiotics and plasma exchange.
The ADAMTS13 level was normal consistent with a diagnosis of aHUS.
The commencement of eculizumab led to the resolution of haemolysis and stabilisation of haemoglobin and platelets with an improvement in renal function.
American Psychological Association (APA)
Inglis, Joshua M.& Barbara, Jeffrey& Juneja, Rajiv& Milton, Caroline& Passaris, George& Li, Jordan Y. Z.. 2018. Atypical Haemolytic Uraemic Syndrome Associated with Clostridium difficile Infection Successfully Treated with Eculizumab. Case Reports in Nephrology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1145182
Modern Language Association (MLA)
Inglis, Joshua M.…[et al.]. Atypical Haemolytic Uraemic Syndrome Associated with Clostridium difficile Infection Successfully Treated with Eculizumab. Case Reports in Nephrology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1145182
American Medical Association (AMA)
Inglis, Joshua M.& Barbara, Jeffrey& Juneja, Rajiv& Milton, Caroline& Passaris, George& Li, Jordan Y. Z.. Atypical Haemolytic Uraemic Syndrome Associated with Clostridium difficile Infection Successfully Treated with Eculizumab. Case Reports in Nephrology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1145182
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145182