Gastric Mucormycosis in a Renal Transplant Patient Treated with Isavuconazole Monotherapy
Joint Authors
Mulloy, Laura L.
Kapoor, Rajan
Gani, Imran
Doroodchi, Atbin
Falkenstrom, Kristina
Berry, Holly
Lee, Won
Saeed, Muhammad
Source
Case Reports in Transplantation
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-17
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Gastrointestinal mucormycosis is a rare infection in solid organ transplant recipients.
Our patient, a 79-year-old male, presented with severe dysphagia and odynophagia about 2 weeks after receiving a renal transplant.
An upper gastrointestinal (UGI) endoscopy revealed esophagitis and gastric ulceration, the cultures from which grew Rhizopus species.
A usual treatment strategy should include Amphotericin B as monotherapy or in combination with Posaconazole or Isavuconazole for such infections.
Our patient was treated with Isavuconazole monotherapy, in an effort to minimize renal toxicity from Amphotericin B to the new allograft.
Unique to our case was a successful clinical response and resolution of UGI lesions with Isavuconazole monotherapy.
Due to the vagueness of presenting symptoms, such infections can be easily missed in an immunocompromised patient which can have tragic outcomes.
Prompt diagnosis and modulation of immunosuppression are essential to decrease mortality and morbidity.
Isavuconazole is a novel agent and can be used as a monotherapy for such infections, especially in renal transplant recipients.
American Psychological Association (APA)
Gani, Imran& Doroodchi, Atbin& Falkenstrom, Kristina& Berry, Holly& Lee, Won& Mulloy, Laura L.…[et al.]. 2019. Gastric Mucormycosis in a Renal Transplant Patient Treated with Isavuconazole Monotherapy. Case Reports in Transplantation،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1145281
Modern Language Association (MLA)
Gani, Imran…[et al.]. Gastric Mucormycosis in a Renal Transplant Patient Treated with Isavuconazole Monotherapy. Case Reports in Transplantation No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1145281
American Medical Association (AMA)
Gani, Imran& Doroodchi, Atbin& Falkenstrom, Kristina& Berry, Holly& Lee, Won& Mulloy, Laura L.…[et al.]. Gastric Mucormycosis in a Renal Transplant Patient Treated with Isavuconazole Monotherapy. Case Reports in Transplantation. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1145281
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145281