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Never Too Old? Occurrence of Medulloblastoma in the Elderly beyond the 70th Year of Life
Joint Authors
Mönninghoff, Christoph
Maslehaty, Homajoun
Van de Nes, Johannes
Teuber-Hanselmann, Sarah
Oezkan, Neriman
Sure, Ulrich
Source
Case Reports in Neurological Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-07
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The occurrence of medulloblastoma (MB) in the elderly is an absolutely rare event.
Concerning this issue we report on two MB patients beyond the 70th year of life.
Two patients older than 70 years presented with a mass in the posterior fossa without evidence of a preexisting malignant tumor.
After careful radiological work-up the suspected diagnosis was metastasis of an unknown primary tumor.
Both patients underwent surgery and histopathological analysis revealed MB in both cases (classical MB and desmoplastic type).
The two cases presented here represent also one classical MB and one additional desmoplastic MB.
To our knowledge we report for the first time that there are different molecular subtypes of MB in the elderly patients that seem to be consistent with those subtypes mainly occurring in young adults.
Unfortunately the patients died within one week after surgery due to respiratory insufficiency and an unclear cause.
The presented cases show that MB can occur in the elderly.
Although this constellation is absolutely rare, MB should be considered in the differential diagnosis, especially when a primary tumor is not known or detected.
American Psychological Association (APA)
Maslehaty, Homajoun& Van de Nes, Johannes& Teuber-Hanselmann, Sarah& Mönninghoff, Christoph& Sure, Ulrich& Oezkan, Neriman. 2018. Never Too Old? Occurrence of Medulloblastoma in the Elderly beyond the 70th Year of Life. Case Reports in Neurological Medicine،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1145491
Modern Language Association (MLA)
Maslehaty, Homajoun…[et al.]. Never Too Old? Occurrence of Medulloblastoma in the Elderly beyond the 70th Year of Life. Case Reports in Neurological Medicine No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1145491
American Medical Association (AMA)
Maslehaty, Homajoun& Van de Nes, Johannes& Teuber-Hanselmann, Sarah& Mönninghoff, Christoph& Sure, Ulrich& Oezkan, Neriman. Never Too Old? Occurrence of Medulloblastoma in the Elderly beyond the 70th Year of Life. Case Reports in Neurological Medicine. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1145491
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145491