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A Case of Recurrent Esophageal Cancer Treated with Concurrent Chemoradiation Therapy in Pregnancy
Joint Authors
Chigusa, Yoshitsugu
Kondoh, Eiji
Mandai, Masaki
Yamada, Kaori
Nomura, Motoo
Sakanaka, Katsuyuki
Nakamura, Mitsuhiro
Yano, Shinsuke
Tsunoda, Shigeru
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Esophageal cancer rarely coincides with pregnancy, and only five cases have been reported thus far.
The management of esophageal cancer during pregnancy is extremely challenging due to its aggressive nature.
We herein report a case of recurrent esophageal cancer in pregnancy.
A 41-year-old multigravida with a history of esophageal squamous cell cancer treated with esophagectomy and perioperative chemotherapy was diagnosed with local recurrent carcinoma of the residual esophagus at 16 weeks of gestation.
The patient strongly desired to continue the pregnancy, and concurrent chemoradiation therapy (CRT) consisting of 50.4 Gy of radiation, cisplatin, and 5-fluorouracil was carried out from 19 weeks of gestation.
CRT was dramatically effective, and the recurrent lesion disappeared.
At 38 weeks of gestation, she underwent cesarean section and delivered a healthy female baby.
Both maternal and fetal courses were satisfactory, and the patient has been free of disease for 12 months.
This is the first case of recurrent esophageal cancer in pregnancy in which CRT was completed without reducing treatment intensity and led to a complete response.
Nevertheless, little is known regarding the safety and possible adverse effects of CRT on the fetus.
Therefore, deliberate selection of patients and long-term follow-up of the child are necessary.
American Psychological Association (APA)
Yamada, Kaori& Chigusa, Yoshitsugu& Nomura, Motoo& Sakanaka, Katsuyuki& Nakamura, Mitsuhiro& Yano, Shinsuke…[et al.]. 2018. A Case of Recurrent Esophageal Cancer Treated with Concurrent Chemoradiation Therapy in Pregnancy. Case Reports in Obstetrics and Gynecology،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1145560
Modern Language Association (MLA)
Yamada, Kaori…[et al.]. A Case of Recurrent Esophageal Cancer Treated with Concurrent Chemoradiation Therapy in Pregnancy. Case Reports in Obstetrics and Gynecology No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1145560
American Medical Association (AMA)
Yamada, Kaori& Chigusa, Yoshitsugu& Nomura, Motoo& Sakanaka, Katsuyuki& Nakamura, Mitsuhiro& Yano, Shinsuke…[et al.]. A Case of Recurrent Esophageal Cancer Treated with Concurrent Chemoradiation Therapy in Pregnancy. Case Reports in Obstetrics and Gynecology. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1145560
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145560