Endometrial Carcinoma in a 26-Year-Old Patient with Bardet-Biedl Syndrome
Joint Authors
Grechukhina, Olga
Gressel, Gregory M.
Munday, William
Wong, Serena
Vash-Margita, Alla
Santin, Alessandro Davide
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-03
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Bardet-Biedl Syndrome (BBS) is a rare genetic condition characterized by cognitive impairment, dysmorphism, central obesity, and diabetes mellitus, among other abnormalities.
Although some of these characteristics are known independent risk factors for endometrial cancer and its precursors, the association between BBS and endometrial cancer is underreported.
Case.
We present the case of a 26-year-old patient with BBS and clinical signs of hyperestrogenism who presented with abnormal uterine bleeding and was diagnosed with endometrioid adenocarcinoma.
She ultimately underwent definitive surgical treatment with hysterectomy and bilateral salpingectomy.
Conclusions.
This is one of only a few reports in the literature describing the association of BBS and endometrioid endometrial adenocarcinoma.
Given the association of BBS with risk factors for hyperestrogenism such as truncal obesity, hyperinsulinemia, and ovulatory dysfunction, providers should have increased suspicion for endometrial cancer in young patients with BBS and abnormal uterine bleeding.
American Psychological Association (APA)
Grechukhina, Olga& Gressel, Gregory M.& Munday, William& Wong, Serena& Santin, Alessandro Davide& Vash-Margita, Alla. 2018. Endometrial Carcinoma in a 26-Year-Old Patient with Bardet-Biedl Syndrome. Case Reports in Obstetrics and Gynecology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1145605
Modern Language Association (MLA)
Grechukhina, Olga…[et al.]. Endometrial Carcinoma in a 26-Year-Old Patient with Bardet-Biedl Syndrome. Case Reports in Obstetrics and Gynecology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1145605
American Medical Association (AMA)
Grechukhina, Olga& Gressel, Gregory M.& Munday, William& Wong, Serena& Santin, Alessandro Davide& Vash-Margita, Alla. Endometrial Carcinoma in a 26-Year-Old Patient with Bardet-Biedl Syndrome. Case Reports in Obstetrics and Gynecology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1145605
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145605