Two Case Reports of Intravenous Leiomyomatosis with Hyaluronan Expression
Joint Authors
Arihiro, Koji
Konishi, Haruhisa
Koh, Iemasa
Shiroma, Noriyuki
Kidani, Yukie
Urabe, Satoshi
Tanaka, Norifumi
Hirata, Eiji
Kudo, Yoshiki
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-17
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Intravenous leiomyomatosis (IVL) is a rare benign neoplasm.
Herein, we describe two cases of IVL at different levels of progression.
The tumor in Case 1 was extensive, invading the right atrium after a hysterectomy for a uterine myoma.
The tumor temporarily responded to hormonal treatment; however, tumor regrowth occurred.
In contrast, the tumor in Case 2 extended only to the pelvic veins and was revealed preoperatively.
Hysterectomy and bilateral salpingo-oophorectomy were performed, resulting in the complete surgical resection of the tumor.
In Case 2, no recurrence has been observed.
Tumor samples were evaluated for hyaluronan expression using Alcian blue staining (with and without hyaluronidase digestion).
The tumor in Case 1 stained strongly positive for hyaluronan while the tumor in Case 2 stained weakly positive for hyaluronan.
In contrast, a large non-IVL uterine leiomyoma (control) stained negative for hyaluronan.
These results suggest a relationship between tumor hyaluronan expression and IVL progression, similar to that in other cancers.
American Psychological Association (APA)
Konishi, Haruhisa& Koh, Iemasa& Shiroma, Noriyuki& Kidani, Yukie& Urabe, Satoshi& Tanaka, Norifumi…[et al.]. 2018. Two Case Reports of Intravenous Leiomyomatosis with Hyaluronan Expression. Case Reports in Obstetrics and Gynecology،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1145705
Modern Language Association (MLA)
Konishi, Haruhisa…[et al.]. Two Case Reports of Intravenous Leiomyomatosis with Hyaluronan Expression. Case Reports in Obstetrics and Gynecology No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1145705
American Medical Association (AMA)
Konishi, Haruhisa& Koh, Iemasa& Shiroma, Noriyuki& Kidani, Yukie& Urabe, Satoshi& Tanaka, Norifumi…[et al.]. Two Case Reports of Intravenous Leiomyomatosis with Hyaluronan Expression. Case Reports in Obstetrics and Gynecology. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1145705
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145705