Thrombotic Microangiopathy Secondary to Intravenous Abuse of Opana® ER
Joint Authors
Thakur, Kamia
Agrawal, Vaibhav
Kass, Ashley
Dimarino, Lauren M.
Dorion, R. Patrick
Vadakara, Joseph
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-18
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Opana ER (oxymorphone) is an opioid drug available throughout the United States, and intravenous abuse of the crushed oral formulation has been associated with drug-induced thrombotic microangiopathy.
In this abstract, we describe two young patients who lived together and used Opana ER intravenously.
Both presented with microangiopathic hemolytic anemia that mimicked thrombotic thrombocytopenic purpura (TTP).
Treating this condition poses a clinical challenge, as it is difficult to distinguish it from TTP.
The role for plasma exchange is not clear but can be used while awaiting the results of the ADAMTS-13 activity, but ultimately supportive care with drug discontinuation is the recommended therapy of choice.
Patients should be counseled against Opana ER’s intravenous use, and users should be offered drug rehabilitation therapy.
American Psychological Association (APA)
Thakur, Kamia& Agrawal, Vaibhav& Kass, Ashley& Dimarino, Lauren M.& Dorion, R. Patrick& Vadakara, Joseph. 2017. Thrombotic Microangiopathy Secondary to Intravenous Abuse of Opana® ER. Case Reports in Hematology،Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1145764
Modern Language Association (MLA)
Thakur, Kamia…[et al.]. Thrombotic Microangiopathy Secondary to Intravenous Abuse of Opana® ER. Case Reports in Hematology No. 2017 (2017), pp.1-3.
https://search.emarefa.net/detail/BIM-1145764
American Medical Association (AMA)
Thakur, Kamia& Agrawal, Vaibhav& Kass, Ashley& Dimarino, Lauren M.& Dorion, R. Patrick& Vadakara, Joseph. Thrombotic Microangiopathy Secondary to Intravenous Abuse of Opana® ER. Case Reports in Hematology. 2017. Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1145764
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145764