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Malignant Transformation of an Ovarian Endometrioma during Endometriosis Treatment: A Case Report
Joint Authors
Takagi, Hiroaki
Takata, Emi
Sakamoto, Jinichi
Fujita, Satoko
Takakura, Masahiro
Sasagawa, Toshiyuki
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-04
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Dienogest (DNG) is considered to be effective against ovarian endometrioma (OMA).
We report a rare case of OMA transformation to ovarian cancer during long-term endometriosis treatment with a periodic administration of a gonadotropin-releasing hormone agonist (Gn-RH agonist) and DNG.
The patient was a 41-year-old Japanese woman.
OMA and adenomyosis of the uterus were revealed via computed tomography.
Consequently, she underwent conservative treatment without undergoing surgery because her overall status was poor.
She received cyclic therapy (Gn-RH agonist and DNG) for approximately eight years.
However, she reported lumbago and underwent close medical examination at our hospital after about eight years of treatment.
Under the suspicion of malignant transformation, she underwent surgery.
The pathological diagnosis was clear cell carcinoma of the right ovary (stage 2B).
After surgery, she received six courses of chemotherapy (conventional TC).
No evidence of disease was observed after chemotherapy.
Our findings suggest that malignant transformation of OMA can occur during DNG treatment.
Since the delayed detection of ovarian cancer greatly affects the prognosis, women older than 40 with OMA are encouraged to undergo regular check-ups every few months.
American Psychological Association (APA)
Takagi, Hiroaki& Takata, Emi& Sakamoto, Jinichi& Fujita, Satoko& Takakura, Masahiro& Sasagawa, Toshiyuki. 2018. Malignant Transformation of an Ovarian Endometrioma during Endometriosis Treatment: A Case Report. Case Reports in Obstetrics and Gynecology،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1145826
Modern Language Association (MLA)
Takagi, Hiroaki…[et al.]. Malignant Transformation of an Ovarian Endometrioma during Endometriosis Treatment: A Case Report. Case Reports in Obstetrics and Gynecology No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1145826
American Medical Association (AMA)
Takagi, Hiroaki& Takata, Emi& Sakamoto, Jinichi& Fujita, Satoko& Takakura, Masahiro& Sasagawa, Toshiyuki. Malignant Transformation of an Ovarian Endometrioma during Endometriosis Treatment: A Case Report. Case Reports in Obstetrics and Gynecology. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1145826
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145826