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Uncovering Clinical Features of De Novo Philadelphia Positive Myelodysplasia
Joint Authors
Mims, Martha
Rivero, Gustavo
Armas Villalba, Aristides
Chen, Chen
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-21
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Myelodysplastic syndrome (MDS) is cytogenetically heterogeneous and retains variable risk for acute myeloid leukemia transformation.
Though not yet fully understood, there is an association between genetic abnormalities and defects in gene expression.
The functional role for infrequent cytogenetic alteration remains unclear.
An uncommon chromosomic abnormality is the presence of the Philadelphia (Ph) chromosome.
Here, we report a patient with Ph+ MDS treated with low dose Dasatinib who achieved hematologic response for 7 months.
In addition, we also examined the English literature on all de novo Ph + MDS cases between 1996 and 2015 to gain insight into clinical features and outcome.
American Psychological Association (APA)
Armas Villalba, Aristides& Chen, Chen& Mims, Martha& Rivero, Gustavo. 2017. Uncovering Clinical Features of De Novo Philadelphia Positive Myelodysplasia. Case Reports in Hematology،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1145895
Modern Language Association (MLA)
Armas Villalba, Aristides…[et al.]. Uncovering Clinical Features of De Novo Philadelphia Positive Myelodysplasia. Case Reports in Hematology No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1145895
American Medical Association (AMA)
Armas Villalba, Aristides& Chen, Chen& Mims, Martha& Rivero, Gustavo. Uncovering Clinical Features of De Novo Philadelphia Positive Myelodysplasia. Case Reports in Hematology. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1145895
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145895