Intermediate-High Risk Pulmonary Embolism: The Use of Riociguat and Inferior Vena Cava Filter in a Situation of Recurrent Embolism following Insufficient Anticoagulation and Fibrinolytic Therapy
Joint Authors
Vo, Anh Khoi
Reikvam, Håkon
Midtbø, Helga
Wirsching, Jan Ludvig
Bruserud, Øyvind
Wendelbo, Øystein
Source
Case Reports in Anesthesiology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Pulmonary embolism (PE) is associated with serious morbidity and mortality.
In this case report, we describe a hemodynamically stable patient with submassive PE and a large thrombus in the inferior vena cava (IVC) protruding into the right atrium (RA), complicated by severe respiratory failure, elevated troponin T (TnT), and right ventricular (RV) dysfunction.
The patient was stratified as intermediate-high risk of early death.
Important issues regarding the initial choice of anticoagulation, rescue thrombolytic therapy, and benefits of adding riociguat to stimulate the nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate (NO-sGC-cGMP) pathway to improve the RV function are discussed.
Finally, we address appropriate timing and the use of IVC filter in a situation of recurrent PE following anticoagulation and fibrinolytic therapy.
American Psychological Association (APA)
Vo, Anh Khoi& Reikvam, Håkon& Midtbø, Helga& Wirsching, Jan Ludvig& Bruserud, Øyvind& Wendelbo, Øystein. 2020. Intermediate-High Risk Pulmonary Embolism: The Use of Riociguat and Inferior Vena Cava Filter in a Situation of Recurrent Embolism following Insufficient Anticoagulation and Fibrinolytic Therapy. Case Reports in Anesthesiology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1145924
Modern Language Association (MLA)
Vo, Anh Khoi…[et al.]. Intermediate-High Risk Pulmonary Embolism: The Use of Riociguat and Inferior Vena Cava Filter in a Situation of Recurrent Embolism following Insufficient Anticoagulation and Fibrinolytic Therapy. Case Reports in Anesthesiology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1145924
American Medical Association (AMA)
Vo, Anh Khoi& Reikvam, Håkon& Midtbø, Helga& Wirsching, Jan Ludvig& Bruserud, Øyvind& Wendelbo, Øystein. Intermediate-High Risk Pulmonary Embolism: The Use of Riociguat and Inferior Vena Cava Filter in a Situation of Recurrent Embolism following Insufficient Anticoagulation and Fibrinolytic Therapy. Case Reports in Anesthesiology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1145924
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145924