Immune-Mediated Autonomic Neuropathies following Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia
Joint Authors
Litzow, Mark R.
Mangaonkar, Abhishek
Duma, Narjust
Khateeb, Hassan Al
Louis, Erik K. St.
McKeon, Andrew
Kourelis, Taxiarchis
Patnaik, Mrinal M.
Hogan, William J.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-27
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background/Aims.
Autonomic dysfunction (AD) after allogeneic stem cell transplant (SCT) is a rare occurrence and likely immune-mediated in etiology.
There is limited literature on this topic and hence, we wish to briefly describe management of two cases at our institution and their outcomes.
Methods.
We retrospectively identified two patients with immune-mediated AD after SCT from our database.
Immune-mediated AD was defined as AD secondary to an immune-mediated etiology without an alternative cause and responding to immunosuppression.
Results.
The first case is of a 32-year-old man with acute myeloid leukemia (AML) who underwent double umbilical cord allogeneic SCT.
The second patient was a 51-year-old woman with secondary AML who underwent matched-related donor allogeneic SCT.
Both underwent an extensive work-up for an underlying etiology prior to treatment with intravenous immunoglobulin (IVIG).
Conclusions.
AD after SCT is a rare yet significant clinical entity.
A work-up of underlying etiology should be performed.
IVIG is a treatment option for these patients.
American Psychological Association (APA)
Mangaonkar, Abhishek& Khateeb, Hassan Al& Duma, Narjust& Louis, Erik K. St.& McKeon, Andrew& Patnaik, Mrinal M.…[et al.]. 2017. Immune-Mediated Autonomic Neuropathies following Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia. Case Reports in Hematology،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1145930
Modern Language Association (MLA)
Mangaonkar, Abhishek…[et al.]. Immune-Mediated Autonomic Neuropathies following Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia. Case Reports in Hematology No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1145930
American Medical Association (AMA)
Mangaonkar, Abhishek& Khateeb, Hassan Al& Duma, Narjust& Louis, Erik K. St.& McKeon, Andrew& Patnaik, Mrinal M.…[et al.]. Immune-Mediated Autonomic Neuropathies following Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia. Case Reports in Hematology. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1145930
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145930