Increased C-Reactive Protein in Brazilian Children: Association with Cardiometabolic Risk and Metabolic Syndrome Components (PASE Study)
Joint Authors
Peluzio, Maria do Carmo Gouveia
Suhett, Lara Gomes
Hermsdorff, Helen Hermana Miranda
Rocha, Naruna Pereira
Silva, Mariane Alves
Filgueiras, Mariana De Santis
Milagres, Luana Cupertino
Novaes, Juliana Farias de
Source
Cardiology Research and Practice
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-16
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
C-reactive protein (CRP) is a marker of subclinical inflammation that has been found to be associated with cardiovascular disease risk.
However, few studies have investigated the relationship between CRP and cardiometabolic markers in a representative sample of prepubescent children.
The objective was to evaluate the high-sensitive CRP (hs-CRP) and its association with traditional and nontraditional cardiometabolic risk factors, as well as metabolic syndrome (MetS) components in Brazilian children.
This is a cross-sectional representative study, with participants of the Schoolchildren Health Assessment Survey (PASE).
Children from 8 to 9 years old (n=350) enrolled in public and private schools in the municipality of Viçosa, Minas Gerais, Brazil, were evaluated.
Sociodemographic evaluation was performed through a semistructured questionnaire.
Anthropometric, body composition, clinical, and biochemical measures were analyzed for cardiometabolic risk assessment.
The total mean of serum hs-CRP concentration was 0.62 (±1.44) mg/L.
hs-CRP was significantly correlated with several anthropometric, biochemical, and clinical parameters in this population (P<0.05).
hs-CRP was positively associated with the accumulation of cardiometabolic risk factors and MetS components (P<0.05).
Children with excessive weight; abdominal obesity; increased gynoid and android body fat; low HDL-c; hyperglycemia; and elevated uric acid, homocysteine, and apoB had higher chances of presenting increased hs-CRP (P<0.05).
In this study, Brazilian children with cardiometabolic risk already presented elevated serum hs-CRP concentration.
hs-CRP was associated with the increase of traditional and nontraditional cardiometabolic risk factors, as well as the accumulation of MetS components.
American Psychological Association (APA)
Suhett, Lara Gomes& Hermsdorff, Helen Hermana Miranda& Rocha, Naruna Pereira& Silva, Mariane Alves& Filgueiras, Mariana De Santis& Milagres, Luana Cupertino…[et al.]. 2019. Increased C-Reactive Protein in Brazilian Children: Association with Cardiometabolic Risk and Metabolic Syndrome Components (PASE Study). Cardiology Research and Practice،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1145949
Modern Language Association (MLA)
Suhett, Lara Gomes…[et al.]. Increased C-Reactive Protein in Brazilian Children: Association with Cardiometabolic Risk and Metabolic Syndrome Components (PASE Study). Cardiology Research and Practice No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1145949
American Medical Association (AMA)
Suhett, Lara Gomes& Hermsdorff, Helen Hermana Miranda& Rocha, Naruna Pereira& Silva, Mariane Alves& Filgueiras, Mariana De Santis& Milagres, Luana Cupertino…[et al.]. Increased C-Reactive Protein in Brazilian Children: Association with Cardiometabolic Risk and Metabolic Syndrome Components (PASE Study). Cardiology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1145949
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1145949