Endogenous Bufadienolides, Fibrosis and Preeclampsia

Joint Authors

Agalakova, Natalia Ivanovna
Reznik, Vitaliy A.
Kashkin, Vladimir A.
Adair, C. David
Bagrov, Alexei Y.

Source

Cardiology Research and Practice

Issue

Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2019-12-12

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Diseases

Abstract EN

Frequency of preeclampsia has no tendency to decrease, and it still takes the leading position in the structure of maternal mortality and morbidity worldwide.

In this review, we present the “fibrotic concept” of the etiology and pathogenesis of preeclampsia which involves system consisting of Na/K-ATPase and its endogenous ligands including marinobufagenin.

New therapy of preeclampsia includes modulation of the Na/K-ATPase system by immunoneutralization of the marinobufagenin and use of mineralocorticoid antagonists which are capable to impair marinobufagenin-Na/K-ATPase interactions.

American Psychological Association (APA)

Reznik, Vitaliy A.& Kashkin, Vladimir A.& Agalakova, Natalia Ivanovna& Adair, C. David& Bagrov, Alexei Y.. 2019. Endogenous Bufadienolides, Fibrosis and Preeclampsia. Cardiology Research and Practice،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1146003

Modern Language Association (MLA)

Reznik, Vitaliy A.…[et al.]. Endogenous Bufadienolides, Fibrosis and Preeclampsia. Cardiology Research and Practice No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1146003

American Medical Association (AMA)

Reznik, Vitaliy A.& Kashkin, Vladimir A.& Agalakova, Natalia Ivanovna& Adair, C. David& Bagrov, Alexei Y.. Endogenous Bufadienolides, Fibrosis and Preeclampsia. Cardiology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1146003

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1146003