Resting Heart Rate and Long-Term Outcomes in Patients with Percutaneous Coronary Intervention: Results from a 10-Year Follow-Up of the CORFCHD-PCI Study
Joint Authors
Zhang, Jinying
Zheng, Ying-Ying
Wu, Ting-Ting
Chen, You
Hou, Xian-Geng
Yang, Yi
Ma, Xiang
Ma, Yi-Tong
Xie, Xiang
Source
Cardiology Research and Practice
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-01
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
The relationship between heart rate in CAD patients who underwent percutaneous coronary intervention (PCI) and had long-term outcomes over up to 10 years of follow-up has not been investigated.
Methods.
All patients were from the CORFCHD-PCI, a retrospective cohort study that included a total of 6050 CAD patients who underwent PCI from January 2008 to December 2016.
One patient was excluded due to a lack of heart rate data.
Ultimately, 6049 patients were enrolled.
The primary outcome was long-term mortality after PCI.
Results.
Patients were divided into 5 groups according to heart rate quintiles: 1st quintile (heart rate <66 beats/min; n=1123), 2nd quintile (heart rate ≥66 beats/min to 72 beats/min; n=1010), 3rd quintile (heart rate ≥72 beats/min to 78 beats/min; n=1442), 4th quintile (heart rate ≥78 beats/min to 84 beats/min; n=1211), and 5th quintile (heart rate ≥84 beats/min; n=1263).
After multivariate Cox regression analyses, the respective risks of ACM, CM, and MACEs were increased 79.1% (hazard risk (HR) = 1.791, 95% CI: 1.207–2.657, P=0.004), 56.9% (HR = 1.569, 95% CI: 1.019–2.416, P=0.041), and 25.5% (HR = 1.255, 95% CI: 0.990–1.590, P=0.060) in the 4th quintile and 98.7% (HR = 1.987, 95% CI: 1.344–2.937, P=0.001), 98.8% (HR = 1.988, 95% CI: 1.310–3.016, P<0.001), and 0.36.1% (HR = 1.361, 95% CI: 1.071–1.730, P=0.012) in the 5th quintile compared with those in the 1st quintile.
Patients with a heart rate of ≥80 beats/min had 89.4%, 115.2%, and 39.1% increased risk of ACM, CM, and MACEs, respectively, compared to those patients with a heart rate of <80 beats/min.
Conclusion.
The present study indicated that the resting heart rate is an independent predictor of adverse long-term outcomes in CAD patients who underwent PCI.
American Psychological Association (APA)
Zheng, Ying-Ying& Wu, Ting-Ting& Chen, You& Hou, Xian-Geng& Yang, Yi& Ma, Xiang…[et al.]. 2019. Resting Heart Rate and Long-Term Outcomes in Patients with Percutaneous Coronary Intervention: Results from a 10-Year Follow-Up of the CORFCHD-PCI Study. Cardiology Research and Practice،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1146011
Modern Language Association (MLA)
Zheng, Ying-Ying…[et al.]. Resting Heart Rate and Long-Term Outcomes in Patients with Percutaneous Coronary Intervention: Results from a 10-Year Follow-Up of the CORFCHD-PCI Study. Cardiology Research and Practice No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1146011
American Medical Association (AMA)
Zheng, Ying-Ying& Wu, Ting-Ting& Chen, You& Hou, Xian-Geng& Yang, Yi& Ma, Xiang…[et al.]. Resting Heart Rate and Long-Term Outcomes in Patients with Percutaneous Coronary Intervention: Results from a 10-Year Follow-Up of the CORFCHD-PCI Study. Cardiology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1146011
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146011