Red Cell Distribution Width as a Novel Marker for Different Types of Atrial Fibrillation in Low and High Altitude
Joint Authors
Han, Kaiyue
Su, Xiaoling
Liu, Jiang
Yao, Fengcai
Lu, FeiYan
Source
Cardiology Research and Practice
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Increased red cell distribution width (RDW) can predict the incidence and mortality of cardiovascular diseases.
However, there are limited data on the relationship between RDW and altitude and the subtype of atrial fibrillation (AF).
We investigated the effects of altitude on RDW in patients with different types of AF.
Methods.
A total of 303 patients with nonvalvular AF were included.
Of these, 156 lived in low altitude (77 paroxysmal AF, PAF; 79 persistent AF, PeAF) and 147 in high altitude (77 paroxysmal AF, PAF; 70 persistent AF, PeAF).
In these groups, baseline characteristics, complete blood counts, serum biochemistry, and echocardiography were evaluated.
Multivariate logistic regression analysis was conducted to determine the independent predictors of AF at the different altitudes.
Results.
In both low and high altitudes, RDW and left atrial diameter (LAD) were higher in AF than control subjects (P<0.05) and higher in persistent AF than paroxysmal AF (P<0.05).
Compared with any groups (PAF group, PeAF group, or control group) of low-altitude, RDW and LAD were found higher in high-altitude corresponding groups.
Multivariate logistic regression analysis demonstrated that RDW, mean corpuscular volume (MCV), and LAD levels independently associated with AF patients in low altitude (RDW, OR 1.687, 95% CI 1.021–2.789; P<0.05), while in high altitude, RDW, MCV, creatinine (Cr), and LAD were independent predictors for AF patients (RDW, OR 1.755, 95% CI 1.179–2.613; P<0.05).
Conclusion.
Elevated RDW levels may be an independent risk marker for nonvalvular AF, affected by type of AF and altitude.
American Psychological Association (APA)
Han, Kaiyue& Su, Xiaoling& Liu, Jiang& Yao, Fengcai& Lu, FeiYan. 2019. Red Cell Distribution Width as a Novel Marker for Different Types of Atrial Fibrillation in Low and High Altitude. Cardiology Research and Practice،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1146032
Modern Language Association (MLA)
Han, Kaiyue…[et al.]. Red Cell Distribution Width as a Novel Marker for Different Types of Atrial Fibrillation in Low and High Altitude. Cardiology Research and Practice No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1146032
American Medical Association (AMA)
Han, Kaiyue& Su, Xiaoling& Liu, Jiang& Yao, Fengcai& Lu, FeiYan. Red Cell Distribution Width as a Novel Marker for Different Types of Atrial Fibrillation in Low and High Altitude. Cardiology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1146032
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146032