Concurrent Hairy Cell Leukemia and Metastatic Merkel Cell Carcinoma
Joint Authors
Prakash, Ajay
Khalafallah, Alhossain A.
Source
Case Reports in Oncological Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-14
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Hairy cell leukemia (HCL) and Merkel cell carcinoma (MCC) are two rare malignancies with distinct cells of origin.
HCL is a lymphoid malignancy of mature B cells, and MCC derives from neuroendocrine cell origin.
HCL has a favorable prognosis with most patients achieving long-term remission and potential cure.
In contrast, MCC is an aggressive malignancy affecting the skin and can metastasize quickly with a dismal prognosis.
Immunocompromised patients, such as those with AIDS, posttransplant, and the elderly, have higher incidences than the general population, suggesting a possible immune mechanism.
We report a case where a patient presented with HCL and metastatic MCC synchronously.
This is the first reported case of these two rare malignancies occurring concurrently at initial presentation and may represent a role of immunosuppression in the pathogenesis of MCC.
American Psychological Association (APA)
Prakash, Ajay& Khalafallah, Alhossain A.. 2018. Concurrent Hairy Cell Leukemia and Metastatic Merkel Cell Carcinoma. Case Reports in Oncological Medicine،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1146113
Modern Language Association (MLA)
Prakash, Ajay& Khalafallah, Alhossain A.. Concurrent Hairy Cell Leukemia and Metastatic Merkel Cell Carcinoma. Case Reports in Oncological Medicine No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1146113
American Medical Association (AMA)
Prakash, Ajay& Khalafallah, Alhossain A.. Concurrent Hairy Cell Leukemia and Metastatic Merkel Cell Carcinoma. Case Reports in Oncological Medicine. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1146113
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146113