Clinical Profile and Outcome in Patients with Coronary Slow Flow Phenomenon
Joint Authors
Zhou, Yujie
Shen, Hua
Zhu, Xiaogang
Gao, Fei
Wu, Sijing
Ma, Qian
Jia, Shuo
Zhao, Ziwei
Tong, Shan
Zhang, Zhihao
Source
Cardiology Research and Practice
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The coronary slow flow phenomenon (CSFP) is a poorly recognized clinical entity characterized by delayed distal vessel opacification in the absence of epicardial coronary stenosis and presently lack of specific data on the clinical profile and outcome.
We investigated a cohort of 429 patients who fulfilled the criteria for CSFP to explore the clinical feature, outcome, and risk factor of prognosis.
Two teams (clinical center and core lab) were blind to patient data for the assessment of coronary angiograph using corrected thrombolysis in myocardial infarction (TIMI) frame count (CTFC).
The study cohort consisted of 429 patients (294 men, 68.5%), aged from 30 to 78 years (mean, 54 years).
Two hundred patients (46.6%) out of 429 patients had a history of hypertension, 72 (16.8%) had diabetes mellitus, and 222 (51.7%) had dyslipidemia.
All the rates of agreement between two teams in evaluating whether normal flow (CTFC ≤ 27 frames) or slow flow (CTFC > 27 frames) were moderate (0.40 < κ < 0.75) for the three arteries.
Follow-up (mean, 3.8 years) was done for 421 patients (98.1%).
The major adverse cardiovascular events (MACE) occurred in 39 patients (9.3%) out of 421 patients.
Multivariate analysis showed that the risk of MACE approximately doubles with age >50 years (hazard ratio (HR) = 2.2, 95% CI: 1.0 to 4.9, and P=0.042), hypertension (HR = 2.1, 95% CI: 1.1 to 4.2, and P=0.021), and dyslipidemia (HR = 2.0, 95% CI: 1.0 to 3.9, and P=0.042).
CSFP affects predominantly patients at middle age and above but can occur in any age group; CSFP should be more concerned, particularly in patients >50 years old with hypertension and dyslipidemia.
American Psychological Association (APA)
Zhu, Xiaogang& Shen, Hua& Gao, Fei& Wu, Sijing& Ma, Qian& Jia, Shuo…[et al.]. 2019. Clinical Profile and Outcome in Patients with Coronary Slow Flow Phenomenon. Cardiology Research and Practice،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1146124
Modern Language Association (MLA)
Zhu, Xiaogang…[et al.]. Clinical Profile and Outcome in Patients with Coronary Slow Flow Phenomenon. Cardiology Research and Practice No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1146124
American Medical Association (AMA)
Zhu, Xiaogang& Shen, Hua& Gao, Fei& Wu, Sijing& Ma, Qian& Jia, Shuo…[et al.]. Clinical Profile and Outcome in Patients with Coronary Slow Flow Phenomenon. Cardiology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1146124
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146124