Acute Stent Thrombosis Associated with Eptifibatide-Induced Profound Thrombocytopenia
Joint Authors
Aljundi, Amer
Rahhal, Alaa
Dabdoob, Wafer
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-10
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Eptifibatide is an inhibitor of the platelet glycoprotein (GP) IIb/IIIa receptor that is commonly used in patients undergoing percutaneous coronary intervention (PCI).
Case.
We describe a case of a 62-year-old female patient admitted with acute ST-elevation myocardial infarction (STEMI) treated by primary coronary intervention (primary PCI) with a drug-eluting stent placement.
She developed profound thrombocytopenia within 8 hours of first administration of eptifibatide and subsequent acute stent thrombosis next day.
Other causes of thrombocytopenia were excluded and intravascular ultrasound (IVUS) showed good stent expansion and opposition to the coronary wall.
Platelet count gradually returned to normal after discontinuation of eptifibatide.
Conclusion.
Although Eptifibatide has been associated with the development of thrombocytopenia, to the best of our knowledge, this is the first case report in the medical literature that associates acute stent thrombosis and eptifibatide-induced thrombocytopenia.
American Psychological Association (APA)
Aljundi, Amer& Rahhal, Alaa& Dabdoob, Wafer. 2020. Acute Stent Thrombosis Associated with Eptifibatide-Induced Profound Thrombocytopenia. Case Reports in Cardiology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1146167
Modern Language Association (MLA)
Aljundi, Amer…[et al.]. Acute Stent Thrombosis Associated with Eptifibatide-Induced Profound Thrombocytopenia. Case Reports in Cardiology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1146167
American Medical Association (AMA)
Aljundi, Amer& Rahhal, Alaa& Dabdoob, Wafer. Acute Stent Thrombosis Associated with Eptifibatide-Induced Profound Thrombocytopenia. Case Reports in Cardiology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1146167
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146167