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Case Reports in Oncological Medicine Myoepithelioma: A New Rearrangement Involving the LPP Locus in a Case of Multiple Bone and Soft Tissue Lesions
Joint Authors
Schubert, Thomas
Galant, Christine
Pairet, Géraldine
Tilman, Gaëlle
Perlepe, Vasiliki
Poirel, Hélène A.
Sciot, Raf
Source
Case Reports in Oncological Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-27
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
We report a case of multiple myoepithelioma with synchronous bone and soft tissue tumors, associated with a new genomic alteration of the LPP locus.
The lesions occurred in the foot by presenting one lump in the plantar soft tissue, and three lesions were detected in the calcaneus and in the navicular bone.
All tumors showed the double immunophenotype of epithelial markers and S100 protein expression.
No rearrangement of the EWSR1 and FUS loci was detected as reported in myoepitheliomas.
However, molecular karyotyping detected an unbalanced rearrangement of the LPP locus, not involving the HMGA2 locus, which is the most frequent translocation partner observed in benign mesenchymal tumors such as lipomas (of soft tissue as well as parosteal) and pulmonary chondroid hamartoma.
American Psychological Association (APA)
Pairet, Géraldine& Tilman, Gaëlle& Sciot, Raf& Schubert, Thomas& Perlepe, Vasiliki& Poirel, Hélène A.…[et al.]. 2018. Case Reports in Oncological Medicine Myoepithelioma: A New Rearrangement Involving the LPP Locus in a Case of Multiple Bone and Soft Tissue Lesions. Case Reports in Oncological Medicine،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1146241
Modern Language Association (MLA)
Pairet, Géraldine…[et al.]. Case Reports in Oncological Medicine Myoepithelioma: A New Rearrangement Involving the LPP Locus in a Case of Multiple Bone and Soft Tissue Lesions. Case Reports in Oncological Medicine No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1146241
American Medical Association (AMA)
Pairet, Géraldine& Tilman, Gaëlle& Sciot, Raf& Schubert, Thomas& Perlepe, Vasiliki& Poirel, Hélène A.…[et al.]. Case Reports in Oncological Medicine Myoepithelioma: A New Rearrangement Involving the LPP Locus in a Case of Multiple Bone and Soft Tissue Lesions. Case Reports in Oncological Medicine. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1146241
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146241