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A Rare Case of Sunitinib-Induced Rhabdomyolysis in Renal Cell Carcinoma
Joint Authors
Liman, Agnes K.
Liman, Andrew D.
Shields, Jenna
Passero, Vida A.
Source
Case Reports in Oncological Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-19
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We report a rare case of metastatic renal cell carcinoma (RCC) in a patient who developed rhabdomyolysis while on sunitinib.
He was admitted to the hospital due to muscle weakness, fatigue, poor oral intake, and difficulty swallowing in March 2017.
He was found to have pancytopenia, liver failure, kidney failure, high uric acid, and increased creatine phosphokinase of more than 5000.
He quickly developed lactic acidosis and acute respiratory failure.
He was transferred to the ICU, but his condition declined rapidly.
He died 3 days later.
In this article we discussed about sunitinib-mediated inhibition of adenosine monophosphate kinase (AMPK) as a possible pathophysiology of rhabdomyolysis.
Our case is the third sunitinib-induced rhabdomyolysis reported in the literature.
American Psychological Association (APA)
Liman, Andrew D.& Passero, Vida A.& Liman, Agnes K.& Shields, Jenna. 2018. A Rare Case of Sunitinib-Induced Rhabdomyolysis in Renal Cell Carcinoma. Case Reports in Oncological Medicine،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1146249
Modern Language Association (MLA)
Liman, Andrew D.…[et al.]. A Rare Case of Sunitinib-Induced Rhabdomyolysis in Renal Cell Carcinoma. Case Reports in Oncological Medicine No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1146249
American Medical Association (AMA)
Liman, Andrew D.& Passero, Vida A.& Liman, Agnes K.& Shields, Jenna. A Rare Case of Sunitinib-Induced Rhabdomyolysis in Renal Cell Carcinoma. Case Reports in Oncological Medicine. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1146249
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146249