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Acute Pancreatitis Induced by Diabetic Ketoacidosis with Major Hypertriglyceridemia: Report of Four Cases
Joint Authors
Bahloul, Mabrouk
Bouaziz, Mounir
Bouchaala, Karama
Bradii, Sabrine
Kallel, Hela
Chtara, Kamilia
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-04
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Acute pancreatitis (AP) is a real clinical challenge.
Acute pancreatitis remains a common cause of emergency department consultations and a major cause for hospitalization.
Gallstones and drinking a lot of alcohol are the most frequent causes of AP.
Moreover, AP can be induced by diabetic ketoacidosis (DKA) complicated by hypertriglyceridemia.
We report 4 cases of DKA with hypertriglyceridemia complicated by AP in previously undiagnosed diabetes patients.
All of our patients presented to the emergency ward with abdominal pain.
Their physical exam showed epigastric tenderness.
An abdominal CT scan was performed for each patient, showing an AP grade E.
Laboratory samples showed high serum glucose levels.
They had metabolic acidosis with elevated anion gap.
They had high lipasemia and amylasemia.
Their lipid panel was disturbed with a high level of cholesterol (from 12.8 mmol/l to 33 mmol/l) and triglyceridemia (from 53 to 133 mmol/l).
Our patients were admitted into our ICU where they received fluid resuscitation and intravenous insulin, and their triglycerides rates decreased gradually.
Two patients recovered to a good health state, and the two others developed septic shock, requiring the use of large-spectrum antibiotics, and acute kidney injury (AKI) with refractory metabolic acidosis, requiring hemodialysis.
Despite the intensive treatment, they developed an unrecoverable multiorgan failure.
Through our case series, we aim to highlight the importance of making an early diagnosis, which can be difficult in some situations due to overlapping signs; however, it is crucial for a good recovery.
A good understanding of the pathway of hypoinsulinemic states causing hypertriglyceridemia then AP is important because it is the key to best management.
American Psychological Association (APA)
Bouchaala, Karama& Bahloul, Mabrouk& Bradii, Sabrine& Kallel, Hela& Chtara, Kamilia& Bouaziz, Mounir. 2020. Acute Pancreatitis Induced by Diabetic Ketoacidosis with Major Hypertriglyceridemia: Report of Four Cases. Case Reports in Critical Care،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1146296
Modern Language Association (MLA)
Bouchaala, Karama…[et al.]. Acute Pancreatitis Induced by Diabetic Ketoacidosis with Major Hypertriglyceridemia: Report of Four Cases. Case Reports in Critical Care No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1146296
American Medical Association (AMA)
Bouchaala, Karama& Bahloul, Mabrouk& Bradii, Sabrine& Kallel, Hela& Chtara, Kamilia& Bouaziz, Mounir. Acute Pancreatitis Induced by Diabetic Ketoacidosis with Major Hypertriglyceridemia: Report of Four Cases. Case Reports in Critical Care. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1146296
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146296