SGLT-2 Inhibitors—a Culprit of Diabetic Ketoacidosis Postbariatric Surgery
Joint Authors
Iqbal, Qasim Zafar
Mishiyev, Danil
Niazi, Muhammad Raphay
Zia, Zeeshan
Sattar, Saud Bin Abdul
Jahanghir, Abdullah
Quyyumi, Shahed
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-05
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Sodium-glucose cotransporter-2 SGLT2 inhibitors are antihyperglycemic drugs that are currently being recommended as second-line therapy for patients with diabetes mellitus.
They have grown increasingly popular over recent years, as they have been shown to have some protective effects on the heart and kidneys, both organ systems that diabetes mellitus has shown to have deleterious effect on over time.
Despite their growing popularity, they have been found to increase the risk of euglycemic diabetic ketoacidosis (DKA).
There is an increasing body of literature detailing cases of euglycemic DKA after bariatric surgery.
We present a case series of three cases of euglycemic DKA postbariatric surgery in patients with an underlying history of type 2 diabetes mellitus, who were being treated with SGLT2 inhibitors prior to the surgery.
All three patients reported to the emergency room with signs, symptoms, and clinical findings of euglycemic DKA.
The AACE recommends SGLT2 inhibitors to be discontinued at least 24 hours prior to surgery and resumed when a patient resumes a normal diet.
Our patients presented with euglycemic DKA after bariatric surgery, and we recommend more research should be done targeted at the prolonged postoperative course of patients on SGLT-2 inhibitors and into creating specific guidelines for their use after bariatric surgery.
American Psychological Association (APA)
Iqbal, Qasim Zafar& Mishiyev, Danil& Niazi, Muhammad Raphay& Zia, Zeeshan& Sattar, Saud Bin Abdul& Jahanghir, Abdullah…[et al.]. 2020. SGLT-2 Inhibitors—a Culprit of Diabetic Ketoacidosis Postbariatric Surgery. Case Reports in Critical Care،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1146308
Modern Language Association (MLA)
Iqbal, Qasim Zafar…[et al.]. SGLT-2 Inhibitors—a Culprit of Diabetic Ketoacidosis Postbariatric Surgery. Case Reports in Critical Care No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1146308
American Medical Association (AMA)
Iqbal, Qasim Zafar& Mishiyev, Danil& Niazi, Muhammad Raphay& Zia, Zeeshan& Sattar, Saud Bin Abdul& Jahanghir, Abdullah…[et al.]. SGLT-2 Inhibitors—a Culprit of Diabetic Ketoacidosis Postbariatric Surgery. Case Reports in Critical Care. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1146308
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146308