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An Extremely Rapid Case of Pneumonitis with the Use of Nivolumab for Pancreatic Adenocarcinoma
Joint Authors
Costa, Rubens Barros
Benson, Al
Yaghmai, Vahid
Costa, Ricardo L. B.
Zhou, Haijun
Behdad, Amir
Kaplan, Jason B.
Sadim, Maureen
Talamantes, Sarah
Kalyan, Aparna
Source
Case Reports in Oncological Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-01
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Pancreatic cancer is the fourth most common cancer death in the United States despite comprising a small percentage of the total number of cancer cases.
The estimated 5-year overall survival (OS) for patients with distant metastatic disease is approximately 3%.
New treatment options are an unmet need and remain an area of active investigation.
A 53-year-old male with metastatic pancreatic cancer presented to the hospital with acute-on-chronic respiratory failure approximately 24 hours after receiving a novel therapeutic combination.
Chest imaging showed marked changes as concerning for pneumonitis.
Infectious workup was negative.
The patient had initial clinical improvement after receiving initial intravenous steroids and oxygen support but eventually deteriorated later opting for supportive measures only.
With infection ruled out, drug-induced pneumonitis was felt to be the likely cause of the radiologic and clinical changes.
The rapidity of onset of symptoms is the aspect being highlighted in this case.
American Psychological Association (APA)
Costa, Rubens Barros& Benson, Al& Yaghmai, Vahid& Costa, Ricardo L. B.& Zhou, Haijun& Behdad, Amir…[et al.]. 2018. An Extremely Rapid Case of Pneumonitis with the Use of Nivolumab for Pancreatic Adenocarcinoma. Case Reports in Oncological Medicine،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1146520
Modern Language Association (MLA)
Costa, Rubens Barros…[et al.]. An Extremely Rapid Case of Pneumonitis with the Use of Nivolumab for Pancreatic Adenocarcinoma. Case Reports in Oncological Medicine No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1146520
American Medical Association (AMA)
Costa, Rubens Barros& Benson, Al& Yaghmai, Vahid& Costa, Ricardo L. B.& Zhou, Haijun& Behdad, Amir…[et al.]. An Extremely Rapid Case of Pneumonitis with the Use of Nivolumab for Pancreatic Adenocarcinoma. Case Reports in Oncological Medicine. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1146520
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146520