Polyneuropathy as Novel Initial Manifestation in a Case of “Nonsecretory” POEMS Syndrome with Sjögren’s Syndrome
Joint Authors
Wan, Wei-Guo
Jiang, Zhixing
Lin, Zhiguang
Chen, Bobin
Liu, Jun
Zou, He-Jian
Liang, Minrui
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) is a paraneoplastic syndrome driven by plasma cell dyscrasias.
We report a patient with novel initial manifestation of polyneuropathy, which was considered due to Sjögren’s syndrome but with poor response to methylprednisolone (120 mg/d) and intravenous immunoglobulin (IVIg).
Further investigation by imaging tests and following biopsy eventually confirmed the diagnosis of POEMS syndrome secondary to solitary plasmocytoma.
To our knowledge, this is the first reported case of POEMS syndrome with Sjögren’s syndrome occurring in the absence of a peripheral monoclonal gammopathy, highlighting the diagnostic challenges posed by this disease and reviewing the diagnostic role of (18) F-FDG PET/CT in POEMS syndrome.
American Psychological Association (APA)
Liang, Minrui& Jiang, Zhixing& Lin, Zhiguang& Chen, Bobin& Zou, He-Jian& Wan, Wei-Guo…[et al.]. 2017. Polyneuropathy as Novel Initial Manifestation in a Case of “Nonsecretory” POEMS Syndrome with Sjögren’s Syndrome. Case Reports in Medicine،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1146562
Modern Language Association (MLA)
Liang, Minrui…[et al.]. Polyneuropathy as Novel Initial Manifestation in a Case of “Nonsecretory” POEMS Syndrome with Sjögren’s Syndrome. Case Reports in Medicine No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1146562
American Medical Association (AMA)
Liang, Minrui& Jiang, Zhixing& Lin, Zhiguang& Chen, Bobin& Zou, He-Jian& Wan, Wei-Guo…[et al.]. Polyneuropathy as Novel Initial Manifestation in a Case of “Nonsecretory” POEMS Syndrome with Sjögren’s Syndrome. Case Reports in Medicine. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1146562
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146562