Malignant Transformation of Testicular Teratoma to PNET, Adenocarcinoma, and Osteosarcoma with Complete Remission after Surgery and Combination Chemotherapy in a Young Adult Male
Joint Authors
Shaw, Angela
Morrell, Miriam
Weissferdt, Annikka
Harrison, Douglas
Hayes-Jordan, Andrea
Source
Case Reports in Oncological Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-03
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Mixed germ cell tumors (GCT) with teratoma components can transform into somatic malignancies which can include histologies outside of traditional germ cell lineages.
We describe a case of an 18-year-old man with a metastatic testicular GCT with both mature and immature teratoma components containing malignant transformation into multiple histologies including PNET in the primary testicular tumor and osteosarcoma in a separate pulmonary metastatic lesion.
Management with targeted chemotherapy resulted in a durable remission.
This is the first reported case that we know of a patient with primary PNET malignant transformation with subsequent metastatic transformation to osteosarcoma.
American Psychological Association (APA)
Shaw, Angela& Morrell, Miriam& Weissferdt, Annikka& Hayes-Jordan, Andrea& Harrison, Douglas. 2018. Malignant Transformation of Testicular Teratoma to PNET, Adenocarcinoma, and Osteosarcoma with Complete Remission after Surgery and Combination Chemotherapy in a Young Adult Male. Case Reports in Oncological Medicine،Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1146628
Modern Language Association (MLA)
Shaw, Angela…[et al.]. Malignant Transformation of Testicular Teratoma to PNET, Adenocarcinoma, and Osteosarcoma with Complete Remission after Surgery and Combination Chemotherapy in a Young Adult Male. Case Reports in Oncological Medicine No. 2018 (2018), pp.1-3.
https://search.emarefa.net/detail/BIM-1146628
American Medical Association (AMA)
Shaw, Angela& Morrell, Miriam& Weissferdt, Annikka& Hayes-Jordan, Andrea& Harrison, Douglas. Malignant Transformation of Testicular Teratoma to PNET, Adenocarcinoma, and Osteosarcoma with Complete Remission after Surgery and Combination Chemotherapy in a Young Adult Male. Case Reports in Oncological Medicine. 2018. Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1146628
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146628
