Isolated Langerhans Cell Histiocytosis of Orbit: A Case Report and Review of the Literature
Joint Authors
Naik, Mayuresh
Mehta, Anuj
Mehrotra, Neha
Solanki, Anil
Source
Case Reports in Ophthalmological Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A 2-year-old male child presented with a painless progressive mass in the inferolateral aspect of right orbit of three-month duration.
Differential leucocyte count revealed raised eosinophil count (13%).
On radiological examination, CT scan showed 25 × 27 mm round well-defined smooth-outlined homogenously enhancing extraconal mass arising from the zygomatic bone at the inferotemporal periorbital area of right orbit with bone erosion.
Histopathological examination of the incision biopsy revealed characteristic Langerhans cells and immunohistochemical studies were positive for S-100 protein and adenosine deaminase.
A diagnosis of Langerhans Cell Histiocytosis (LCH) was made and PET-CT revealed no other foci of uptake anywhere else in the body.
The patient received 12 cycles of vinblastine, 0.2 mg/kg body weight, along with oral prednisolone, 1 mg/kg body weight.
On completion of three cycles of chemotherapy, a reduction in size of the mass was noticed.
A repeat PET scan was done 3 months after completion of chemotherapy did not reveal any activity noted previously.
American Psychological Association (APA)
Naik, Mayuresh& Mehta, Anuj& Mehrotra, Neha& Solanki, Anil. 2018. Isolated Langerhans Cell Histiocytosis of Orbit: A Case Report and Review of the Literature. Case Reports in Ophthalmological Medicine،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1146716
Modern Language Association (MLA)
Naik, Mayuresh…[et al.]. Isolated Langerhans Cell Histiocytosis of Orbit: A Case Report and Review of the Literature. Case Reports in Ophthalmological Medicine No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1146716
American Medical Association (AMA)
Naik, Mayuresh& Mehta, Anuj& Mehrotra, Neha& Solanki, Anil. Isolated Langerhans Cell Histiocytosis of Orbit: A Case Report and Review of the Literature. Case Reports in Ophthalmological Medicine. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1146716
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146716