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Simultaneous Left Ventricular and Deep Vein Thrombi Caused by Protein C Deficiency
Joint Authors
Maki, Harufumi
Nishiyama, Motohiro
Shirakawa, Motoaki
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-17
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Protein C deficiency is a risk of venous thrombosis because of poor fibrinolytic activity.
It remains controversial whether protein C deficiency causes arterial thrombosis.
A 21-year-old woman was referred with a chief complaint of right leg pain and numbness.
Contrast-enhanced computed tomography revealed a low-density mass in the left ventricle (LV), splenic infarction, and peripheral arterial obstructions in her right leg.
Thrombosis extending from the renal vein to the inferior vena cava was also detected.
Electrocardiography revealed ST depression in leads II, III, and aVF.
Transthoracic echocardiography revealed hypokinesis of the apex and interventricular septum and a hypoechoic mass in the LV (26 × 20 mm).
She was diagnosed with acute arterial obstruction caused by the LV thrombus, which might have resulted from previous myocardial infarction.
Protein C activation turned out to be low (41%) 5 days after admission.
The anticoagulant therapy was switched from heparin to rivaroxaban 16 days after admission.
The LV thrombus disappeared 24 days after initial treatment, and she has had no thrombotic episodes for 2.8 years under rivaroxaban therapy.
Thrombophilia should be investigated for cases of simultaneous left ventricular and deep venous thrombi.
Rivaroxaban can be effective in prevention of further thrombotic events.
American Psychological Association (APA)
Maki, Harufumi& Nishiyama, Motohiro& Shirakawa, Motoaki. 2017. Simultaneous Left Ventricular and Deep Vein Thrombi Caused by Protein C Deficiency. Case Reports in Medicine،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1146719
Modern Language Association (MLA)
Maki, Harufumi…[et al.]. Simultaneous Left Ventricular and Deep Vein Thrombi Caused by Protein C Deficiency. Case Reports in Medicine No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1146719
American Medical Association (AMA)
Maki, Harufumi& Nishiyama, Motohiro& Shirakawa, Motoaki. Simultaneous Left Ventricular and Deep Vein Thrombi Caused by Protein C Deficiency. Case Reports in Medicine. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1146719
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146719