Delayed Healing of Tooth Extraction Sockets with Ramucirumab Use
Joint Authors
Horie, Norio
Yamada, Miki
Hino, Shunsuke
Iijima, Yosuke
Kaneko, Takahiro
Sano, Motohiko
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objective.
An angiogenesis inhibitor can cause medication-related osteonecrosis of the jaw (MRONJ).
To our knowledge, there has been no report that an angiogenesis inhibitor causes delayed healing of tooth extraction socket.
Here, we describe a case of delayed healing of tooth extraction sockets associated with an angiogenesis inhibitor, ramucirumab, which showed characteristics similar to MRONJ.
Materials and Methods.
A 76-year-old male patient, who was diagnosed with gastric cancer with liver metastasis, received tooth extraction twice during continuous chemotherapy comprising paclitaxel and ramucirumab.
Results.
The first extraction was performed 30 days after ramucirumab discontinuation without complication.
The second extraction was conducted without ramucirumab discontinuation.
Although tooth socket healing was finally achieved, it took about 150 days.
Discussion.
This case was considered to be delayed healing of dry sockets rather than MRONJ due to ramucirumab.
Dentists and oral surgeons need to be aware that angiogenesis inhibitors can cause not only MRONJ but also dry sockets after tooth extraction.
American Psychological Association (APA)
Iijima, Yosuke& Yamada, Miki& Hino, Shunsuke& Sano, Motohiko& Kaneko, Takahiro& Horie, Norio. 2020. Delayed Healing of Tooth Extraction Sockets with Ramucirumab Use. Case Reports in Dentistry،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1146768
Modern Language Association (MLA)
Iijima, Yosuke…[et al.]. Delayed Healing of Tooth Extraction Sockets with Ramucirumab Use. Case Reports in Dentistry No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1146768
American Medical Association (AMA)
Iijima, Yosuke& Yamada, Miki& Hino, Shunsuke& Sano, Motohiko& Kaneko, Takahiro& Horie, Norio. Delayed Healing of Tooth Extraction Sockets with Ramucirumab Use. Case Reports in Dentistry. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1146768
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146768