Anaphylactoid Purpura Associated with Streptococcal Cellulitis: A Case Report and Literature Review

Abstract EN

A 54-year-old Japanese man noticed painful swelling and redness of his left leg.

He was admitted for treatment of cellulitis, which was accompanied with increased anti-streptolysin O and anti-streptokinase titers in his clinical course.

After Piperacillin/Tazobactam administration, the skin lesion resolved.

However, the patient then developed arthritis, palpable purpura, and intermittent abdominal pain, later found to be secondary to a severe duodenal ulcer.

He was diagnosed with cellulitis-associated anaphylactoid purpura and was given prednisolone, which dramatically improved his symptoms.

The anaphylactoid purpura was likely caused by Streptococcus-induced cellulitis, which was successfully treated with prednisolone.

Association between these diseases is rare.