The Utility of Major Salivary Gland Ultrasonographic Parameters in the Diagnosis of Sjögren Syndrome
Joint Authors
Caraba, Alexandru
Babalic, Flavia Corina
Iurciuc, Stela
Iurciuc, Mircea
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
To investigate ultrasonographically the salivary glands and to correlate ultrasonographic parameters with focus score, serum beta-2-microglobulin, and stimulated salivary flow rate.
Material and Methods.
32 patients with primary Sjögren’s syndrome (pSS) and 32 healthy controls were enrolled in this case-control study, performed in the Department of Internal Medicine, Division of Rheumatology, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania.
All the patients and controls were examined by salivary gland ultrasonography (B-mode, color and spectral Doppler, and sonoelastography), determining the following parameters: salivary gland ultrasonography (SGUS) score, resistive index (RI) of transverse facial artery, and shear wave velocity (SWV).
Serum beta-2-microglobulin and stimulated saliva amount were determined in all the patients and controls.
Minor salivary gland biopsy with focus score assessment was done in pSS patients.
Results.
Patients with pSS presented higher SGUS score and parotid and submandibular SWV and reduced RI of transverse facial artery than controls (p<0.0001).
In pSS patients, statistically significant correlations were identified between assessed ultrasonographic parameters and focus score, serum beta-2-microglobulin, and respective stimulated saliva flow (p<0.0001).
Conclusions.
This study highlighted statistically significant correlations between salivary gland ultrasonographic parameters and focus score, serum beta-2-microglobulin, and stimulated saliva flow.
American Psychological Association (APA)
Caraba, Alexandru& Babalic, Flavia Corina& Iurciuc, Stela& Iurciuc, Mircea. 2019. The Utility of Major Salivary Gland Ultrasonographic Parameters in the Diagnosis of Sjögren Syndrome. Disease Markers،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1146895
Modern Language Association (MLA)
Caraba, Alexandru…[et al.]. The Utility of Major Salivary Gland Ultrasonographic Parameters in the Diagnosis of Sjögren Syndrome. Disease Markers No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1146895
American Medical Association (AMA)
Caraba, Alexandru& Babalic, Flavia Corina& Iurciuc, Stela& Iurciuc, Mircea. The Utility of Major Salivary Gland Ultrasonographic Parameters in the Diagnosis of Sjögren Syndrome. Disease Markers. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1146895
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146895