EpCAMlow Circulating Tumor Cells: Gold in the Waste
Joint Authors
Nicolazzo, Chiara
Gradilone, Angela
Raimondi, Cristina
Gazzaniga, Paola
Loreni, Flavia
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-17
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The CellSearch® system which is still considered the gold standard for the enumeration of circulating tumor cells (CTC) utilizes antibodies against the epithelial cell adhesion molecule (EpCAM) for CTC enrichment.
Recently, CTC discarded by the CellSearch® system due to their low EpCAM expression have been isolated and analyzed.
We here sought to discuss technical and biological issues concerning the isolation and characterization of EpCAMlow CTC, highlighting the enormous potential of this subpopulation discarded by CellSearch®, which might instead reveal an unexpected clinical significance in tumor types where CTC enumeration has never been validated for prognostic and predictive purpose.
American Psychological Association (APA)
Nicolazzo, Chiara& Gradilone, Angela& Loreni, Flavia& Raimondi, Cristina& Gazzaniga, Paola. 2019. EpCAMlow Circulating Tumor Cells: Gold in the Waste. Disease Markers،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1146899
Modern Language Association (MLA)
Nicolazzo, Chiara…[et al.]. EpCAMlow Circulating Tumor Cells: Gold in the Waste. Disease Markers No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1146899
American Medical Association (AMA)
Nicolazzo, Chiara& Gradilone, Angela& Loreni, Flavia& Raimondi, Cristina& Gazzaniga, Paola. EpCAMlow Circulating Tumor Cells: Gold in the Waste. Disease Markers. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1146899
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146899
