Pentraxin-3 Levels Relate to the Wells Score and Prognosis in Patients with Acute Pulmonary Embolism
Joint Authors
Xu, Yawei
Guo, Rong
Yang, Haotian
Zhang, Jun
Huan, Ying
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To investigate the value of the PTX-3 test in evaluating the prognosis of acute pulmonary embolism (APE).
Method.
117 APE patients were selected and divided into two groups according to plasma PTX-3 levels, including the group in which PTX−3≥3.0 ng/mL (n=42) and the group in which PTX−3<3.0 ng/mL (n=75).
Patients were stratified into high-risk, medium-risk, and low-risk groups according to the Wells scores, and the PTX-3 levels were compared among the groups.
Patients had been followed-up as well.
Results.
According to the Wells scores, 11 patients were classified as high-risk (9.4%) and 68 were medium-risk (58.1%), while 38 were low-risk (32.5%).
The PTX-3 levels in different risk groups were statistically different (all P<0.05).
During the follow-up period, 6 deaths occurred in the group with elevated PTX-3 (≥3.0 ng/mL), while 2 deaths occurred in the group with nonelevated PTX-3 (<3.0 ng/mL).
The difference between the two groups was statistically significant (P<0.01).
13 patients were hospitalized due to recurrent pulmonary embolism, of which 12 were in the group with elevated PTX-3 (≥3.0 ng/mL), while 1 patient was in the group with nonelevated PTX-3 (<3.0 ng/mL).
The difference was statistically significant (P<0.01).
Conclusion.
The plasma PTX-3 level in APE patients is correlated with PE risk stratification.
There is a significant correlation between PTX-3 levels and PE-related cardiac deaths, as well as the prognosis of recurrent PE.
PTX-3 can be used as a clinical indicator of PE prognosis.
American Psychological Association (APA)
Yang, Haotian& Zhang, Jun& Huan, Ying& Xu, Yawei& Guo, Rong. 2019. Pentraxin-3 Levels Relate to the Wells Score and Prognosis in Patients with Acute Pulmonary Embolism. Disease Markers،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1146944
Modern Language Association (MLA)
Yang, Haotian…[et al.]. Pentraxin-3 Levels Relate to the Wells Score and Prognosis in Patients with Acute Pulmonary Embolism. Disease Markers No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1146944
American Medical Association (AMA)
Yang, Haotian& Zhang, Jun& Huan, Ying& Xu, Yawei& Guo, Rong. Pentraxin-3 Levels Relate to the Wells Score and Prognosis in Patients with Acute Pulmonary Embolism. Disease Markers. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1146944
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146944