A Case of Proliferative Glomerulonephritis with Monoclonal IgG Deposits That Showed Predominantly Membranous Features
Joint Authors
Hirayama, Kouichi
Shimohata, Homare
Ohgi, Kentaro
Maruyama, Hiroshi
Miyamoto, Yasunori
Takayashu, Mamiko
Kobayashi, Masaki
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-25
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
In 2004, the novel category of monoclonal IgG deposition disease has been proposed and termed “proliferative glomerulonephritis with monoclonal IgG deposits” (PGNMID).
This disease is characterized by membranoproliferative glomerulonephritis and staining for a single light-chain isotype and gamma heavy-chain subclass.
A 76-year-old male who had monoclonal gammopathy was referred to our hospital because of proteinuria.
The renal biopsy showed diffuse thickening of the glomerular capillary walls with focal mesangial proliferation.
On immunofluorescence study, only IgG1 among the four subclasses and lambda light chains were detected mainly in the glomerular capillary walls.
From these results, we diagnosed our case as PGNMID showing predominantly membranous features.
Almost all pathological findings on light microscopy of PGNMID are membranoproliferative GN or endocapillary proliferative GN, while membranous GN cases are rare.
Here, we present the case of PGNMID that showed predominantly membranous features on light microscopy.
American Psychological Association (APA)
Shimohata, Homare& Ohgi, Kentaro& Maruyama, Hiroshi& Miyamoto, Yasunori& Takayashu, Mamiko& Hirayama, Kouichi…[et al.]. 2017. A Case of Proliferative Glomerulonephritis with Monoclonal IgG Deposits That Showed Predominantly Membranous Features. Case Reports in Nephrology،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1146947
Modern Language Association (MLA)
Shimohata, Homare…[et al.]. A Case of Proliferative Glomerulonephritis with Monoclonal IgG Deposits That Showed Predominantly Membranous Features. Case Reports in Nephrology No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1146947
American Medical Association (AMA)
Shimohata, Homare& Ohgi, Kentaro& Maruyama, Hiroshi& Miyamoto, Yasunori& Takayashu, Mamiko& Hirayama, Kouichi…[et al.]. A Case of Proliferative Glomerulonephritis with Monoclonal IgG Deposits That Showed Predominantly Membranous Features. Case Reports in Nephrology. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1146947
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146947