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Vitamin D-Resistant Rickets Diagnostics and Treatment Challenges at Muhimbili National Hospital, Tanzania
Joint Authors
Manji, K. P.
Godfrey, Evance K.
Mussa, Fatima
Kazahura, Parvina
Shoo, Aika
Naburi, Helga
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction.
Rickets is softening of bones caused by defective mineralization of the cartilage in the epiphyseal growth plate, causing widening of the ends of long bones, growth retardation, and skeletal deformities in children.
It can be classified into calciopenic and phosphopenic, each type with various subclasses.
Case Presentations.
We presented 2 cases, first of a 1 year and 4-month-old male, with a history of recurrent episodes of cough for 8 months and bowing of the legs 6 months prior to admission.
Clinical and laboratory investigation was suggestive of vitamin D-dependent rickets, and he started vitamin D treatment with minimal response.
The second case is of a 4 years and 7-month-old male who presented with developmental delay, poor weight gain, and recurrent chest infection and worsening of bone pain since 9 months of age.
Laboratory investigation was suggestive of phosphopenic rickets, and he was started on treatment at 9 months of age with little improvement and at 4 years, he sustained multiple fractures and succumbed to severe respiratory tract infection and died at 4 years and 7 months of age.
Conclusion.
Rickets pose a diagnostic and treatment challenge in resource-limited countries, and clinical judgment and early initiation of treatment are important.
American Psychological Association (APA)
Godfrey, Evance K.& Mussa, Fatima& Kazahura, Parvina& Shoo, Aika& Naburi, Helga& Manji, K. P.. 2020. Vitamin D-Resistant Rickets Diagnostics and Treatment Challenges at Muhimbili National Hospital, Tanzania. Case Reports in Endocrinology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1146954
Modern Language Association (MLA)
Godfrey, Evance K.…[et al.]. Vitamin D-Resistant Rickets Diagnostics and Treatment Challenges at Muhimbili National Hospital, Tanzania. Case Reports in Endocrinology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1146954
American Medical Association (AMA)
Godfrey, Evance K.& Mussa, Fatima& Kazahura, Parvina& Shoo, Aika& Naburi, Helga& Manji, K. P.. Vitamin D-Resistant Rickets Diagnostics and Treatment Challenges at Muhimbili National Hospital, Tanzania. Case Reports in Endocrinology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1146954
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146954