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Delayed Manifestation of Shunt Nephritis: A Case Report and Review of the Literature
Joint Authors
Werner, Sherry L.
Babigumira, Michael
Huang, Benjamin
Qunibi, Wajeh
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-09
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
We present an unusual case of shunt nephritis in a 39-year-old male who presented 21 years after placement of a ventriculoperitoneal (VP) shunt.
He complained of fevers, headaches, dizziness, and urticarial plaques on arms, trunks, and legs and was found to have anemia, low complement levels, elevated serum creatinine, proteinuria, and new onset microhematuria.
Blood and urine cultures were negative.
Renal biopsy showed features of acute tubulointerstitial nephritis attributed to vancomycin use.
Glomeruli showed increased mesangial hypercellularity and segmental endocapillary proliferation.
Immunofluorescence showed focal IgM and C3 staining.
Electron microscopy revealed small subendothelial electron-dense deposits.
Symptoms and renal insufficiency appeared to improve with antibiotic therapy.
He was discharged and readmitted 2 months later with similar presentation.
CSF grew Propionibacterium acnes and shunt hardware grew coagulase-negative Staphylococcus.
He completed an intravenous antibiotic course and was discharged.
On 1-month follow-up, skin lesions persisted but he was otherwise asymptomatic.
Follow-up labs showed significant improvement.
We did a brief systematic review of the literature on shunt nephritis and report our findings on 79 individual cases.
In this review, we comment on the presentation, lab findings, pathological features, and management of this rare, potentially fatal, but curable disease entity.
American Psychological Association (APA)
Babigumira, Michael& Huang, Benjamin& Werner, Sherry L.& Qunibi, Wajeh. 2017. Delayed Manifestation of Shunt Nephritis: A Case Report and Review of the Literature. Case Reports in Nephrology،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1146973
Modern Language Association (MLA)
Babigumira, Michael…[et al.]. Delayed Manifestation of Shunt Nephritis: A Case Report and Review of the Literature. Case Reports in Nephrology No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1146973
American Medical Association (AMA)
Babigumira, Michael& Huang, Benjamin& Werner, Sherry L.& Qunibi, Wajeh. Delayed Manifestation of Shunt Nephritis: A Case Report and Review of the Literature. Case Reports in Nephrology. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1146973
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1146973