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Acute Hypocalcemia and Metabolic Alkalosis in Children on Cation-Exchange Resin Therapy
Joint Authors
Pradhan, Madhura
Kakajiwala, Aadil
Barton, Kevin T.
Rampolla, Elisha
Breen, Christine
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-01
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Sodium polystyrene sulfonate (SPS) is a chelating agent used for the treatment of hyperkalemia.
SPS has a wide range of exchange capacity requiring close monitoring of serum electrolytes.
We observed two patients who developed acute hypocalcemia and increased metabolic alkalosis after initiating SPS therapy.
We report these cases to draw attention to the potential risk of this medication in pediatric patients.
Case Diagnosis/Treatment.
Two children with chronic kidney disease on dialysis were started on SPS for hyperkalemia.
Within a week after initiation of the medication, both patients developed hypocalcemia on routine labs without overt clinical manifestations.
The hypocalcemia was rapidly corrected with oral supplementation and discontinuation of SPS.
Conclusions.
Severe hypocalcemia can develop after SPS therapy.
The metabolic alkalosis in these patients associated with the hypocalcemia put them at increased risk for complications.
Hence, careful attention must be paid to the state of calcium metabolism in all patients receiving SPS.
Often calcium supplementation is required to maintain normal calcium levels.
American Psychological Association (APA)
Kakajiwala, Aadil& Barton, Kevin T.& Rampolla, Elisha& Breen, Christine& Pradhan, Madhura. 2017. Acute Hypocalcemia and Metabolic Alkalosis in Children on Cation-Exchange Resin Therapy. Case Reports in Nephrology،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1147002
Modern Language Association (MLA)
Kakajiwala, Aadil…[et al.]. Acute Hypocalcemia and Metabolic Alkalosis in Children on Cation-Exchange Resin Therapy. Case Reports in Nephrology No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1147002
American Medical Association (AMA)
Kakajiwala, Aadil& Barton, Kevin T.& Rampolla, Elisha& Breen, Christine& Pradhan, Madhura. Acute Hypocalcemia and Metabolic Alkalosis in Children on Cation-Exchange Resin Therapy. Case Reports in Nephrology. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1147002
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147002