Critical Low Catastrophe: A Case Report of Treatment-Refractory Hypoglycemia following Overdose of Long-Acting Insulin
Joint Authors
Sandooja, Rashi
Moorman, John M.
Priyadarshini Kumar, Monisha
Detoya, Karla
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-19
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Overdose of long-acting insulin can cause unpredictable hypoglycemia for prolonged periods of time.
The initial treatment of hypoglycemia includes oral carbohydrate intake as able and/or parenteral dextrose infusion.
Refractory hypoglycemia following these interventions presents a clinical challenge in the absence of clear guidelines for management.
Octreotide has sometimes been used, but its use is generally limited to sulfonylurea overdose.
In this case report, we present a case of refractory hypoglycemia following an overdose of 900 units of long-acting insulin glargine that failed to respond to usual modes of therapy mentioned above.
Stress-dose corticosteroids were then initiated, followed by subsequent improvement in IV dextrose and glucagon requirements and blood glucose levels.
Hence, corticosteroids may serve as an adjunctive therapy in managing hypoglycemia and can be considered earlier in the course of treatment in patients with refractory hypoglycemia to prevent volume overload, especially when large volumes of dextrose infusions are required.
American Psychological Association (APA)
Sandooja, Rashi& Moorman, John M.& Priyadarshini Kumar, Monisha& Detoya, Karla. 2020. Critical Low Catastrophe: A Case Report of Treatment-Refractory Hypoglycemia following Overdose of Long-Acting Insulin. Case Reports in Endocrinology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147130
Modern Language Association (MLA)
Sandooja, Rashi…[et al.]. Critical Low Catastrophe: A Case Report of Treatment-Refractory Hypoglycemia following Overdose of Long-Acting Insulin. Case Reports in Endocrinology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1147130
American Medical Association (AMA)
Sandooja, Rashi& Moorman, John M.& Priyadarshini Kumar, Monisha& Detoya, Karla. Critical Low Catastrophe: A Case Report of Treatment-Refractory Hypoglycemia following Overdose of Long-Acting Insulin. Case Reports in Endocrinology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147130
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147130