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Levodopa Responsive Parkinsonism in Patients with Hemochromatosis: Case Presentation and Literature Review
Joint Authors
Sidiropoulos, Christos
Girotra, Tarun
Mahajan, Abhimanyu
Source
Case Reports in Neurological Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-23
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Hemochromatosis is an autosomal recessive disorder which leads to abnormal iron deposition in the parenchyma of multiple organs causing tissue damage.
Accumulation of iron in the brain has been postulated to be associated with several neurodegenerative diseases including Parkinson’s disease.
The excess iron promotes Parkin and α-synuclein aggregation in the neurons.
Excess iron has also been noted in substantia nigra on MRI especially using susceptibility weighted imaging in patients with Parkinson’s disease.
We present a case of a young male with alleles for both C282Y and H63D who presented with signs of Parkinsonism and demonstrated significant improvement with levodopa treatment.
American Psychological Association (APA)
Girotra, Tarun& Mahajan, Abhimanyu& Sidiropoulos, Christos. 2017. Levodopa Responsive Parkinsonism in Patients with Hemochromatosis: Case Presentation and Literature Review. Case Reports in Neurological Medicine،Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147155
Modern Language Association (MLA)
Girotra, Tarun…[et al.]. Levodopa Responsive Parkinsonism in Patients with Hemochromatosis: Case Presentation and Literature Review. Case Reports in Neurological Medicine No. 2017 (2017), pp.1-3.
https://search.emarefa.net/detail/BIM-1147155
American Medical Association (AMA)
Girotra, Tarun& Mahajan, Abhimanyu& Sidiropoulos, Christos. Levodopa Responsive Parkinsonism in Patients with Hemochromatosis: Case Presentation and Literature Review. Case Reports in Neurological Medicine. 2017. Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147155
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147155