HMGB1 as a Potential Biomarker and Therapeutic Target for Malignant Mesothelioma
Joint Authors
Ying, Shibo
Yan, Jianing
Wang, Yanbin
Jiang, Zhaoqiang
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-12
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Malignant mesothelioma (MM) is a rare, aggressive, and highly lethal cancer that is substantially induced by exposure to asbestos fibers.
High-mobility group box 1 (HMGB1) is an intriguing proinflammatory molecule involved in MM.
In this review, we describe the possible crucial roles of HMGB1 in carcinogenic mechanisms based on in vivo and in vitro experimental evidence and outline the clinical findings of epidemiological investigations regarding the possible roles of HMGB1 as a biomarker for MM.
We conclude that novel strategies targeting HMGB1 may suppress MM cells and interfere with asbestos-induced inflammation.
American Psychological Association (APA)
Wang, Yanbin& Jiang, Zhaoqiang& Yan, Jianing& Ying, Shibo. 2019. HMGB1 as a Potential Biomarker and Therapeutic Target for Malignant Mesothelioma. Disease Markers،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1147181
Modern Language Association (MLA)
Wang, Yanbin…[et al.]. HMGB1 as a Potential Biomarker and Therapeutic Target for Malignant Mesothelioma. Disease Markers No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1147181
American Medical Association (AMA)
Wang, Yanbin& Jiang, Zhaoqiang& Yan, Jianing& Ying, Shibo. HMGB1 as a Potential Biomarker and Therapeutic Target for Malignant Mesothelioma. Disease Markers. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1147181
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147181
