Magnetic Resonance Imaging in Pregnancy with Intrauterine Growth Restriction: A Pilot Study
Joint Authors
Buonocore, Giuseppe
Santacroce, Antonino
de Bernardo, Giuseppe
Alagna, Maria Gabriella
Paternò, Irene
Carbone, Salvatore Francesco
Perrone, Serafina
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
Intrauterine growth restriction (IUGR) is a major cause of late stillbirth, though not all compromised babies remain small or are considered growth restricted as pregnancy progresses.
Fetal Magnetic Resonance Imaging (f-MRI) represents a second-line tool to study pregnancies with IUGR fetuses.
The aim of our study was to evaluate the usefulness of f-MRI on predicting fetal growth and the offspring’s perinatal respiratory outcome.
Design.
All f-MRI performed between 2014 and 2016 in Siena were analysed.
Pregnancies with IUGR (Study group (SG)) were recruited together with a control population (Control group (CG)), coupled for gestational age (GA) at the time of f-MRI (mean GA 31 wks).
Neonatal information was collected.
The f-MRI protocol consisted of T2w images.
Six regions of interest (ROI) were placed as follows: 2 on the lung, 2 on the liver, and 2 on the amniotic fluid.
The signal intensities (SI) of each ROI were measured.
The SI lung to liver ratio (SI lung/liver) and SI lung to amniotic fluid ratio (SI lung/amniotic fluid) were obtained for each fetus.
Each ratio was compared between SG and CG.
Therefore, SG was divided into two subgroups: adequate and small for gestational age (AGA and SGA) newborns.
All measurements were related to offspring’s perinatal respiratory outcome.
Results.
SI lung/liver was linearly related with GA at the time of f-MRI and with EFW.
SI lung/amniotic fluid was significantly higher in SG than in CG (p=0,014).
In contrast, among SG, lower values of SI lung/amniotic fluid were found in the SGA compared to AGA (p=0,036).
The days of oxygen supply were higher in the SGA subgroup than in the AGA subgroup (p=0,028).
Conclusions.
SI lung/liver increases with fetal lung maturation and appears to be useful to estimate intrauterine fetal growth.
SI lung/amniotic fluid seems to be a reliable predictive index to distinguish the IUGR fetuses that can recover their growth from those that were born SGA.
f-MRI represents a promising frontier to predict IUGR fetus outcome, thus contributing to ameliorate the perinatal management.
American Psychological Association (APA)
Perrone, Serafina& Santacroce, Antonino& de Bernardo, Giuseppe& Alagna, Maria Gabriella& Carbone, Salvatore Francesco& Paternò, Irene…[et al.]. 2019. Magnetic Resonance Imaging in Pregnancy with Intrauterine Growth Restriction: A Pilot Study. Disease Markers،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1147191
Modern Language Association (MLA)
Perrone, Serafina…[et al.]. Magnetic Resonance Imaging in Pregnancy with Intrauterine Growth Restriction: A Pilot Study. Disease Markers No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1147191
American Medical Association (AMA)
Perrone, Serafina& Santacroce, Antonino& de Bernardo, Giuseppe& Alagna, Maria Gabriella& Carbone, Salvatore Francesco& Paternò, Irene…[et al.]. Magnetic Resonance Imaging in Pregnancy with Intrauterine Growth Restriction: A Pilot Study. Disease Markers. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1147191
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147191