Endocervical Carcinogenesis and HPV Vaccination: An Occasional Circumstance or a Gap in the Chain?
Joint Authors
Sergentanis, Theodoros N.
Karakitsos, Petros
Margari, Niki
Chrelias, Charalampos
Makris, George Marios
Battista, Marco Johannes
Papantoniou, Nikolas
Kotsifa, Eugenia
Poulakaki, Nikiforita
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-01
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
As a result of the Human Papillomavirus (HPV) vaccination program, the prevalence of precancerous dysplasia and invasive cervical cancer has substantially decreased.
In this brief report, we present a case of a young patient who was diagnosed with in situ adenocarcinoma of the cervix.
This 30-year-old female had completed the HPV vaccination after she became sexually active and has been undergoing annual gynecological assessments, including clinical examination and Pap test, all of which had been negative.
This year, her Pap test revealed a low grade squamous intraepithelial lesion (LGSIL) and additionally a colposcopy was performed.
Given the extent of the lesion and since the colposcopy was inadequate, the patient underwent a type 3 large loop excision of the transformation zone and a curettage of the endocervix under local anesthesia.
The pathological diagnosis from cervical biopsy revealed an in situ adenocarcinoma of the endocervix with negative limits.
The HPV subtypes 16 and 83 were detected with PCR.
After proper consultation she decided to preserve her fertility and to undergo a regular follow-up, postponing hysterectomy after the completion of her family planning.
In conclusion, this case report highlights the need for diagnostic surveillance regarding HPV-related cervical cancer even after vaccination.
American Psychological Association (APA)
Makris, George Marios& Karakitsos, Petros& Kotsifa, Eugenia& Margari, Niki& Poulakaki, Nikiforita& Sergentanis, Theodoros N.…[et al.]. 2017. Endocervical Carcinogenesis and HPV Vaccination: An Occasional Circumstance or a Gap in the Chain?. Case Reports in Obstetrics and Gynecology،Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147389
Modern Language Association (MLA)
Makris, George Marios…[et al.]. Endocervical Carcinogenesis and HPV Vaccination: An Occasional Circumstance or a Gap in the Chain?. Case Reports in Obstetrics and Gynecology No. 2017 (2017), pp.1-3.
https://search.emarefa.net/detail/BIM-1147389
American Medical Association (AMA)
Makris, George Marios& Karakitsos, Petros& Kotsifa, Eugenia& Margari, Niki& Poulakaki, Nikiforita& Sergentanis, Theodoros N.…[et al.]. Endocervical Carcinogenesis and HPV Vaccination: An Occasional Circumstance or a Gap in the Chain?. Case Reports in Obstetrics and Gynecology. 2017. Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147389
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147389